Medico Research Chronicles 2024-02-22T13:22:25+0530 Dr. Bindu Jain Open Journal Systems <p style="text-align: justify;"><code></code><strong>Medico Research Chronicles (Medrech) ISSN No. 2394-3971</strong>, as the official journal of Medico Edge Publications, serves as a catalyst for advancing medical and health sciences. With its commitment to excellence, the journal invites diverse manuscripts that contribute to the ever-evolving landscape of medical, health science, and clinical research. Through its rigorous peer review process, open-access policy, and timely publication, Medico Research Chronicles continues to be a trusted platform for researchers and practitioners, driving innovation and shaping the future of healthcare.</p> <p>Indexed by the&nbsp;&nbsp;<a href=""><strong>United States'&nbsp;NLM Catalogue, NCBI</strong></a></p> <p><strong><a href=";lang=pl">Index Copernicus</a>, </strong>Medico Research Chronicles, the esteemed journal of Medico Edge Publications, has received a positive evaluation from Index Copernicus, Poland for the year 2021. With an impressive IC Value of 84.43, the journal reaffirms its position as a reputable platform for groundbreaking research in the field of medical and health sciences. This recognition underscores the journal's commitment to scientific excellence and its significant contribution to advancing healthcare knowledge. Researchers and practitioners can rely on Medico Research Chronicles as a trusted source of innovative research findings.</p> <p><strong>Academicians and Researchers interested in reviewing the article are requested to join us on Publons: <a title="Publons by Web of Science" href=""></a></strong></p> <p><strong><a href="">Click Here </a></strong>for the notification details.</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;</p> Spectrum of neurological disorders in children with neonatal hypoglycemia of western rural Maharashtra. 2024-02-16T23:25:52+0530 Dr. Jukanti Venkatasai Krishna Rao Dr. P. V. Nigwekar Dr. Jayashree. P. Jadhav <p>Background: Glucose is an essential metabolic fuel for the brain, and in the newborn the proportionately large brain accounts for almost all of total tissue glucose requirements. Neonatal hypoglycemia is not timely and properly treated, the infants may develop permanent brain injury. Persistent or recurrent hypoglycemia may lead to long-term visual disturbance, hearing impairment, cognitive abnormalities, secondary epilepsy, and other disorders in the central nervous system. Aims and objectives: To study the clinical profile of hypoglycemia in high-risk newborns, as well as neurological squeal. Methods: This is a descriptive cross sectional study was conducted at the department of pediatrics, Dr. Vitthalrao Vikhe Patil Pravara Rural hospital Loni, Maharastra, India, performed on children aged 3 months to 12 years coming to Paediatrics neurology OPD from Feb 2022 to Dec 2023. Results: Out of 60 patients 31(51.6%) presented with seizures. Global developmental delay is found in children, out of which - gross motor delay in 28 (46.67%), fine motor delay in 29(48.33%), social milestone delay in 18(30%) and language mile stone delay in 18(30%) children. 6 (10%)children had autism spectrum disorders. Vision impairment is seen in 36(60%) cases which have significant p value of 0.042. Out of 60 children, 26(43.33%) undergone MRI brain of which in 23(88.46%) of the cases MRI brain was abnormal. Conclusion: Neonatal hypoglycemia is the most common condition in neonatal critical care units, with a significant morbidity rate during infancy and childhood in the form of developmental delay, epilepsy, vision abnormalities, hearing abnormalities and autism etc. It is important to regularly follow these babies for neurodevelopmental assessment to detect and monitor sequalae like developmental delay, epilepsy, visual impairment etc. so as to start early intervention therapy for better neurodevelopmental outcome.</p> 2023-12-21T00:00:00+0530 Copyright (c) The Prevalence, Diagnosis, and Management of Voice Disorders in a Single Center Study 2024-02-22T13:10:26+0530 Sazedul Islam Md. Kamruzaman Md. Mostafizur Rahman M. H. Mahmud Moriam Pervin <p><strong>Background:</strong> Vocal disorders are challenging medical conditions to research nationally. Vocal disorders are a diverse collection of complaints based on symptoms, unlike other system-based illnesses that have well-defined pathologic, laboratory, or objective diagnostic criteria. No specialized national database or agency is in place to gather information on patients with voice problems. Large-scale epidemiologic studies that examine the prevalence, contributing causes, and available treatments for voice disorders are therefore uncommon. Objectives: This study was done to evaluate the prevalence, diagnosis, and management of voice disorders in a single center study. <strong>Methods: </strong>The cross-sectional study was conducted in the Department of ENT, Prime Medical College Rangpur from June 2021 to May 2022. A total of 60 subjects of both sexes were included in the study. Data were collected by face-to-face interview and analyzed by appropriate computer based programmed software Statistical Package for the Social Sciences (SPSS), version 22. <strong>Results: </strong>In this study, most of the patient 16 (26.6%) lies between 41 years to 50 years and about 38 (63.30%) patients were female and 22 (36.70%) patients were male. About 19 (31.7%) patients had acute condition and 24 (40.0%) had chronic condition. Most of the patients 73.3% had asthma, about 70% patients had respiratory allergy. About 38 (63.3%) had smoking habit and 22 (36.7%) patients were non-smoker. Most of the patients 37 (78.3%) had no family history of voice disorder and 13 (21.6%) had the family history. <strong>Conclusion: </strong>According to the current study, a significant proportion of VC patients' diagnostic and treatment programs nationwide are in accordance with established guidelines. To improve care for patients with vocal issues, doctors of various specialties should be aware of these recommendations.</p> Copyright (c) 2023 Sazedul Islam, Md. Kamruzaman, Md. Mostafizur Rahman, M. H. Mahmud, Moriam Pervin Role of prophylactic antibiotic of single dose versus multiple doses in uncomplicated groin Hernia Surgery 2024-02-22T13:22:25+0530 Md. Arshad Ali Sazedul Islam Mohammad Salauddin Omar M. H. Mahmud Anjana Sarker Farzana Hoque <p><strong>Background:</strong> Surgical site infection is the most common complication encountered in inguinal hernia (IH) surgery. Antibiotic prophylaxis for groin hernia surgery may limit wound infection. However, there is a debate to use in general. <strong>Objectives:</strong> The aim of this study is to compare the effect of prophylactic single dose versus multiple doses antibiotic in uncomplicated groin hernia patients were admitted in a tertiary care hospital. <strong>Methods:</strong> This randomized clinical trial was conducted for twenty-four months in the department of Surgery of Rangpur Medical College and Hospital. A total of 132 patients with uncomplicated groin hernia were included after considering the inclusion and exclusion criteria. Informed written consent was obtained from the participants. Ethical clearance was obtained before beginning of the study from the ERC. Detailed history was taken and clinical examination was done. Patients were randomly divided into two groups. Group A received antibiotic prophylaxis of single dose and Group B received multiple doses antibiotic. Patients were followed up at 3<sup>rd</sup> and 5<sup>th</sup> postoperative day and surgical site infection was evaluated by ASEPSIS scoring system. Statistical analyses of the results were be obtained by using window-based Microsoft Excel and Statistical Packages for Social Sciences (SPSS-24). <strong>Results:</strong> The mean age of the patients was 48.94±10.04 and 50.26±10.37 years in group A and B accordingly. Male predominance was observed in both groups A and B. Age and gender was statistically similar in both groups. Surgical site infection was significantly high among patients who received multiple doses antibiotic (9.09% Vs 6.06%). Group A patients were discharged comparatively early than group B patients with statistical significance. Mean hospital stay was also longer in group B patients than group A patients (3.93±1.41 days Vs 3.34±1.41 days). <strong>Conclusion:</strong> Present study findings indicate that surgical site infections could be reduced by using a prophylactic single dose antibiotic prior to surgical treatment for uncomplicated inguinal hernia. But before finalizing the comment, further larger study is recommended.</p> 2023-12-22T00:00:00+0530 Copyright (c) 2023