Medico Research Chronicles <p style="text-align: justify;"><code></code>Medico Research Chronicles (Medrech) ISSN No. <a href="">2394-3971</a>, is an official journal of Medico Edge Publications. It is a peer-reviewed, open-access journal of medical and health sciences, published on bi-monthly intervals. It publishes various manuscripts on the diverse specialization of medical, health science, and clinical research.</p> <p>Indexed by the&nbsp;&nbsp;<a href=""><strong>United States'&nbsp;NLM Catalogue, NCBI</strong></a></p> <p><strong>Medico Research Chronicles has been positively evaluated by <a href=";lang=pl">Index Copernicus</a>, Poland for the year 2020 and assigned an IC Value of 81.95</strong></p> <p><strong>Journal is valid for publication as per MCI Guidelines. A transitory period of 2 years (Upto 2022) is given for consideration of publication.&nbsp;</strong></p> <p><strong>Academicians and Researchers interested in reviewing the article are requested to join us on Publons: <a title="Publons by Web of Science" href=""></a></strong></p> <p><strong><a href="">Click Here </a></strong>for the notification details.</p> <p>&nbsp;</p> Medico Edge Publications en-US Medico Research Chronicles 2394-3971 Evaluation of illizarov technic in treating tibial open fractures: An observational study <p><strong>I</strong><strong>ntroduction: </strong>Illizarov technique is a versatile method of treating open tibial fractures after debridement and open reduction. Tibial open fractures are usually classified into Type I, II, IIIA, IIIB and IIIC. Illizarov method has many advantages and features for such fracture treatment. But in Bangladesh, we have not enough research-oriented information regarding this treatment method.</p> <p><strong>Aim of the study: </strong>This study aimed to assess the Ilizarov technique in treating tibial open fractures.</p> <p><strong>Methods:</strong> This observational prospective study was conducted in the Department of Orthopedics of TMSS Medical College, Bogura, Bangladesh and 3 associated private clinics during the period from January 2018 to December 2021. In total 23 patients with tibial open fractures were confirmed as the study subjects. Before starting this 3 year in3-yeartion, proper written consent of the participants was taken and this study was approved by the ethical committee of the mentioned hospital and clinics. A semi-structured; pre-designed questionnaire was used in collecting patient data. All the data were processed, analyzed and disseminated by using MS Office and SPSS version 23.&nbsp;&nbsp;</p> <p><strong>Results:</strong> In this study, we found highest 65% of participants were injured from road traffic accidents (RTA) followed by 26% from general falls and the rest 9% from a sports injury as the mode of injury. The total treatment duration with the fixator was 12-23 weeks with an average of 16 weeks. The operation time ranged from 90 minutes to 120 minutes. As per the Karlstrom and Olerud criteria, the highest 70% of patients got ‘excellent’ results. Besides this, 17%, 9% and 4% of patients got ‘good’, ‘fair’ and ‘poor’ results respectively.</p> <p><strong>Conclusion:</strong> In our study, we found some excellent features the of Ilizarov induced method in the treatment of open fractures of tibia. We would like recommend more use of Ilizthe arov technic in the field of Orthopaedics.</p> A.K.M. Shaharul Islam Md. Qumruzzaman Parvez Md. Rifat Munzoor-Al-Mahmud Kh. Nafiz Rahman Copyright (c) 2022 Dr. A.K.M. Shaharul Islam, Dr. Md. Qumruzzaman Parvez, Dr. Md. Rifat Munzoor-Al-Mahmud, Dr. Kh. Nafiz Rahman 2022-05-10 2022-05-10 9 3 158 164 10.26838//MEDRECH.2022.9.3.594 Clinical outcome and risk factors of patients with acute myocardial infarction: A tertiary level hospital-based study in Bangladesh. <p><strong>I</strong><strong>ntroduction:</strong> Coronary Artery Disease (CAD) remains the major cause of mortality and morbidity in mankind. Even though a lot of advances are made in the diagnosis, management, and prevention of the disease. Coronary Artery Disease (CAD) is the leading cause of death in the United States, affecting over 5 million Americans. It is the most common cause of death worldwide.</p> <p><strong>Aim of the study:</strong> The study aimed to evaluate the clinical outcome and Risk Factors of Patients with Acute Myocardial Infarction in a Tertiary Level Hospital-Based Study in Bangladesh.</p> <p><strong>Methods: </strong>This cross-sectional study was conducted in the Department of Cardiology, TMC &amp; RCH, Bogura, Bangladesh from January 2020 to January 2021. The study was conducted after obtaining ethical clearance from the institutional review board of TMC &amp; RCH, Bogura, Bangladesh. The data was collected from the discharge records of the patients admitted to the cardiology department.</p> <p><strong>Result:</strong> A total of 56 patients were diagnosed with myocardial infarction and analyzed in this study.&nbsp; The age distribution of the study was based on STEMI, 22(39.39%) patients suffering from AMI were in the 50-59 years age group, 16(28.57%) patients were from the age group 60-69, 12(21.43%) patients were from the age group 40-49, among the 5(8.93%) patients were from the age group &gt;70 age group and only one patient was from the age group 30-39. the clinical outcomes of the study population; there are 17(30.36%) patients who had a cardiogenic shock, 13(23.21%) patients who were getting well, 12(21.43%) patients who had LVF/Pulmonary edema, 7(12.50%) patients had bradyarrhythmias and both 7(12.50%) patients died within 24 hours of hospital admission, 5(8.93%) patients have had tachyarrhythmias, 4(7.14%) patients had a cardiac arrest and only one patient had a mechanical complication.</p> <p><strong>Conclusion:</strong> There is a need for early detection of risk factors to prevent the progression of coronary heart disease, a need for creating awareness in the community regarding risk factors, symptoms, and signs of acute myocardial infarction so that early referral can be done to the coronary care unit to prevent morbidity and mortality in the community.</p> Md. Younus Ali Md. Mahfuzul Islam Md. Shahadat Hussain Kowshik Bhowmick Md. Abdur Rob Rayhan Sadequl Islam Maskurul Alam Copyright (c) 2022 Dr. Md. Younus Ali, Dr. Md. Mahfuzul Islam, Dr. Md. Shahadat Hussain, Dr. Kowshik Bhowmick, Dr. Md. Abdur Rob Rayhan, Dr. Sadequl Islam, Dr. Maskurul Alam 2022-05-27 2022-05-27 9 3 172 179 10.26838/MEDRECH.2022.9.3.599 Ischemic Stroke and its associated factors among Adult patients at public referral hospitals, in Addis Ababa, Ethiopia <p><strong>Background</strong><strong>:</strong> Stroke is a chronic non-communicable disease resulting from infractions or spontaneous hemorrhage in the brain. The burden of stroke is increasing at an alarming rate globally. In 2013 there were 6.5 million stroke deaths, and 113 million disability-adjusted life years due to stroke from this, 75.2% of all stroke mortality and 81.0% of stroke-related disability-adjusted life years are from developing countries. Ischemic stroke is the most common form of stroke approximately about 80%–85% of all strokes in nature. Stroke Deaths in Ethiopia reached 7% of total deaths. It is decreasing in the developed countries while it is increasing in low level and middle-income countries. This study aims to assess ischemic stroke and associated factors among four selected hospitals in Addis Ababa Ethiopia</p> <p><strong>Methods</strong><strong>: </strong>Hospitals-based cross-sectional study design was conducted among 159 stroke patients’ who were attending at four selected hospitals in Addis Ababa, Ethiopia May 1/2019 to April 30/2020. Information on relevant variables was collected from adult stroke patients’ paper-based medical records and registries. The study period was from December 2020 to June 2020.&nbsp; Using a systematic random sampling technique 159 were included in this study. Record review was used to collect data and it was entered and analyzed by using SPSS version 24. Variables with a p-value less than 0.25 in bivariable logistic regression were selected for multivariable logistic regression. The adjusted odds ratio and 95% confidence interval were used to determine the association. P-value &lt;0.05 was used to declare statistical significance in multivariable analysis.&nbsp;&nbsp;&nbsp;</p> <p><strong>Result:</strong> 159 adult stroke patients were included in the study with that 156 (98.11%) response rates. Out of the total 156 patients, 31 (19.9 %%) died and the remaining 125 (80.1%) were improved. The mean (SD) age of the study patient was 54.84+17.12 years. The prevalence of ischemic stroke was 81 (51.92%), [95% CI, 41-55.8] with the determinant risk factors of ischemic stroke were hypertension (AOR= 4.49, 95% CI: 1.89-10.67) followed by Atrial fibrillation (AOR=8.08, 95% CI: 2.50-26.12) and valvular heart disease (AOR=3.07, 95% CI: 1.34-7.01) were the significant association of ischemic stroke. <em>&nbsp;</em></p> Getasew Mulatu Aknaw Alemshet Yirga Berhie Yordanos Elias Bezabih Copyright (c) 2022 Getasew Mulatu Aknaw, Alemshet Yirga Berhie, Yordanos Elias Bezabih 2022-06-08 2022-06-08 9 3 180 190 10.26838/MEDRECH.2022.9.3.600 Clinical profile and outcome of patients with diabetic foot infection: A single centre study <p><strong>Introduction</strong>: Diabetes mellitus with its limb and life-threatening complication such as diabetic foot infection and amputation are increasing at epidemic rates all over the world.</p> <p><strong>Aim of the study:</strong> The study aims to find out the clinical profile and outcomes of patients with diabetic foot infections (DFI).</p> <p><strong>Methods:</strong> This was a prospective study conducted at a tertiary care institute. A total of 82 patients were included and analyzed in this study from January 2020 to December 2022. This study recruited patients &gt;18 years of age, with DFI. All patients underwent a detailed history and clinical examination. Patients were classified as per the International Working Group on the Diabetic Foot -IDSA classification. The patients were followed up every month for 3 months. Clinical outcome was studied regarding the rate of amputations, readmissions, and mortality.</p> <p><strong>Result:</strong> A total of 82 patients were included and analyzed in this study. There are 36 (43.90%) patients from the age range 55-65 which is height and the lowest is 2(2.44%) patients from the age range 15-24. The ulcer healing during follow-up of the study, the mean±SD of the baseline is 14.85±23.12. After 1 month the percentage of wound healing is 20.88% and the mean±SD is 11.75±22.68, after 2 months the percentage of wound healing is 43.16% and the mean±SD is 8.44±22.05 and after 3 months the percentage of wound healing is 57.04% and the mean±SD is 6.38±21.19. The p-value of follow-up duration is equal to &lt;0.001 which was shown as a significant change.</p> <p><strong>Conclusion:</strong> This study shows the predominance of monomicrobial growth and Gram-negative organisms in diabetic foot patients. With the increase in the severity of DFI, there was an increased rate of hospital readmissions, amputations (major and minor), and mortality. Dimensions of the ulcer may have a bearing on the rate of minor amputations.</p> Anirudha Sardar Asadullahil Galib Polash Kumar Dey A. K. M. Lutful Haque Md. Mahmudul Hasan Copyright (c) 2022 Dr. Anirudha Sardar, Dr. Asadullahil Galib, Dr. Polash Kumar Dey, Dr. A. K. M. Lutful Haque, Dr. Md. Mahmudul Hasan 2022-06-24 2022-06-24 9 3 191 199 10.26838/MEDRECH.2022.9.3.601 Acinic Cell Carcinoma: Case Report <p>We report on a 57-year-old male patient who was referred to an oral medicine specialist following an incidental finding of a buccal swelling. The patient presented with a swelling in the left buccal region of five years duration, not associated with pain or trauma. Patient gave no history of purulent discharge in the oral cavity, loss of appetite or loss of weight. Examination of the left buccal region revealed a firm non-tender mobile attached swelling of size 18 X 20 mm on the left buccal mucosa.&nbsp; Left parotid gland duct orifice was normal. Rest of the oral cavity was found normal with no evidence of cervical lymphadenopathy. The treatment of choice was complete surgical excision followed with 3 monthly follow-ups.</p> Nabil Khzam Alissa Jacobs Copyright (c) 2022-05-23 2022-05-23 9 3 165 171 10.26838/MEDRECH.2022.9.3.595