Medico Research Chronicles

Relationship between Clinical Features and Ultrasonographic Findings in Knee Osteoarthritis

Dr. A. M Anisul Islam — 2025-06-16

Introduction: One of the leading causes of disability and morbidity is knee Osteoarthritis. Clinical symptoms, careful examination, and radiographic evidence like Magnetic Resonance Imaging diagnose knee OA. MRI is expensive and scarce, but MSK USG is cheaper and more accessible, especially in peripheral locations. Thus, this study examined the link between clinical characteristics and ultrasonographic data in knee OA patients to simplify investigation.

Methods: The Department of Physical Medicine and Rehabilitation and Department of Radiology and Imaging, Dhaka Medical College Hospital (DMCH), Dhaka collaborated on this cross-sectional study. The trial lasted a year. This study comprised 90 knee OA patients who met inclusion and exclusion criteria. Participants gave written informed consent. Every patient had a complete history and clinical evaluation. WOMAC measured pain, stiffness, and physical function. X-rays and MSK US were done on each patient. Data were gathered by questionnaire. The data was analyzed using SPSS 23.

Results: The mean age of responders was 50.9±7.6 (SD) years, with a 4:6 male-female ratio. The mean WOMAC scores for pain, stiffness, and physical function were 10.7±2.2, 3.7±2.4, and 41.3±5.3, respectively MSK US showed osteophytes in 76.7%, effusion in 51.1%, articular cartilage degeneration in 35.6%, and power dropler change in 37.8%. These features were significantly linked to KLS grading (X-ray) and WOMAC scores (Pain & stiffness) (p<.05).

Conclusion: This study observed significant positive association between MSK US findings and clinical features among patients with knee OA. Sill, further larger study is recommended.

Femoral Neck System (FNS): A Biomechanical Strong Solution for Stable Fixation in Basi cervical Neck of Femur Fractures

Dr. Muhammad Hasnat — 2025-05-28

Background: Due to their rarity and probable instability, basicervical femoral neck fractures whose frequency ranges from 1.8 to 7.6% present difficulties and have higher repair failure rates than intertrochanteric fractures. Even though the fracture site is extracapsular, surgical treatment is still difficult. Objectives: This study was done for assessment of femoral neck system (FNS) as a biomechanical strong solution for stable fixation in basicervical neck of femur fractures. Methods: The cross-sectional Observational study was conducted in the Department of Orthopedic, National Institute of Traumatology and Orthopedic Rehabilitation (NITOR) from June 2022 to May 2023. A total of 30 patients of both sexes were included in the study. Data was collected over a period of 12 months and analyzed by appropriate computer based programmed software Statistical Package for the Social Sciences (SPSS), version 24. Results: In this study, most of the respondents 18 (60.7%) lies between 51 years to 60 years. Mean ± SD of the respondents was 52.41 ± 6.75 years. More than half of the patient 19 (63.30%) were male and 11 (36.70%) patients were female. Most of the patients 17 (56.7%) BMI were in between normal range, 7 (23.3%) were underweight and 6 (20.0%) were overweight. Mean ± SD of the patients BMI was 25.3 ± 5.4 kg/m2. About 12 (40.0%) patients had type III garden fracture, 9 (30.0%) patients had type II garden fracture, and 9 (30.0%) patients had type I garden fracture. Most of the patients 21 (70.0%) had type II Pauwels fracture. The average surgery time was 76.65 ± 34.25 min, the blood loss was 67.45 ± 51.43 ml, the Preoperative Harris Score was 22.25 ± 4.56 and the Postoperative Harris Score was 83.80 ± 5.78, the healing time was 3.33 ± 0.60 and Femoral neck shortens was 2.20 ± 1.41mm. Non-union had occurred in case of 3 (10.0%) patients, Femoral neck shortening had occurred in 2 (6.7%) case and Femoral neck necrosis had occurred in 1 (3.3%) case. Conclusion: FNS treatment can produce good clinical outcomes for patients with basi cervical femoral neck fractures. FNS exhibits much greater overall construct stability and superior biomechanical qualities. Key words: Femoral neck system, Femoral neck fracture, Harris Hip Score, Surgical fixation devices

An Analysis of Risk Factors and Clinical Outcomes of Choledocholithiasis in Patients at a Tertiary Care Hospital in Bangladesh.

Dr. Mohammad Syedul Islam — 2025-05-28

Background: Choledocholithiasis is a common biliary disorder characterized by the presence of stones in the common bile duct, leading to significant clinical complications and morbidity. This study aims to investigate the clinical profile, risk factors, and symptoms of patients diagnosed with choledocholithiasis at a tertiary care hospital in Bangladesh, with an emphasis on demographic patterns and associated comorbid conditions.

Methods: This cross-sectional study was conducted at Bangladesh Medical University (BMU) between July 2024 and December 2024, involving 170 patients diagnosed with choledocholithiasis. Data were collected through a detailed review of clinical records, which included demographic information, clinical features, lifestyle factors, comorbidities, and symptoms. Patients were also assessed for risk factors such as diet, physical activity, and body composition.

Results: The study sample primarily consisted of patients aged 41-60 years (27.65%), with a female predominance (58.83%). Common risk factors included a non-vegetarian diet (57.64%), a sedentary lifestyle (56.47%), and obesity (48.23%). Comorbidities, including diabetes mellitus (38.82%) and hypertension (32.94%), were also prevalent in the patient population. The most frequently reported symptoms were pain (80%), jaundice (71.76%), and fever (52.94%). Clinical signs, such as tenderness in the right hypochondriac region (91.76%) and icterus (89.41%), were predominant.

Conclusion: This study provides a comprehensive overview of the clinical characteristics and risk factors associated with choledocholithiasis in Bangladesh. The findings suggest the need for targeted interventions to address lifestyle factors, manage comorbidities, and consider gender-based risk stratification in clinical practice. Further studies are needed to assess the long-term impact of these factors on disease progression and patient outcomes.