CLINICAL UTILITY OF CAT SCORE IN PATIENTS WITH COPD EXACERBATION AND STABLE DISEASE AND ITS CORRELATION WITH PULMONARY FUNCTION TESTS: AN OBSERVATIONAL PROSPECTIVE STUDY

  • Dr. R. J. Khyalappa Professor & Head, Dept. of Medicine, D. Y. Patil Hospital & Research Institute, Kolhapur
  • Dr. S. M. Thanekar Post Graduate Student, Dept. of Medicine, D. Y. Patil Hospital & Research Institute, Kolhapur
Keywords: COPD, PFT, CAT Score

Abstract

Background: Burden of COPD is on rising and is a common cause of hospitalization and mortality. Presently Pulmonary Function Tests (PFT) is the common diagnostic tool as well as tool for assessing severity of COPD. However, PFT are not routinely available at Primary Health Centre. Present research aims to study clinical utility of CAT score for assessing COPD severity so that it can be used where PFT is unavailable.

Materials & Methods: Aim of this study was to assess the correlation between CAT score and PFT parameters in stable COPD and its exacerbation. 50 patients from both form of the disease were included in the study. CAT score was noted & PFT was performed for stable COPD patients during their routine OPD visit and at day1 & day5 for those requiring hospitalization for COPD exacerbation.

Observations: We found significant difference between each study group (Stable COPD patients, Day1 of COPD exacerbation and Day5 of COPD exacerbation) in all three parameters i.e. CAT score, FEV1 (%pred) and FVC (%pred) (p<0.05). CAT score also correlates with the change in FEV1 (%pred) and FVC (%pred) during a COPD exacerbation. Also, there was negative correlation between FEV1 (%pred) and FVC (%pred) with CAT score in stable COPD patients.

Conclusion: CAT scores correlates with PFT parameters in stable COPD as well as acute exacerbation of COPD.

Outcome: CAT score can be utilized to assess the severity of COPD especially in resource limited setups where there is no facility for Pulmonary Function Testing and also it is cost effective.

Downloads

Download data is not yet available.

References

1. WHO Factsheet. Chronic obstructive pulmonary disease (COPD). WHO, Geneva, Switzerland 1 December 2017 available at https://www.who.int/newsroom/fact-sheets/detail/chronicobstructive-pulmonary-disease-(COPD). Accessed on 7 Oct 2018.
2. Colin D. Mathers, Dejan Loncar. Projections of Global Mortality and Burden of Disease from 2002 to 2030. November 2006; Volume 3, Issue 11, e442
3. Global Initiative for Chronic Obstructive Lung Diseases. Pocket guide to COPD diagnosis, management and prevention. A Guide for Health care Professions. 2018 edition. Available at https://goldcopd.org/wpcontent/uploads/2018/02/WMS-GOLD-2018-Feb-Final-to-print-v2.pdf. Accessed on 05 December 2018.
4. Toshita Kalkana et. al. Increasing burden of COPD in rural India: an example why India warrants primary healthcare reforms. ERJ Open Res 2016; 2: 00032-2016
5. Cooper, Christopher B. Assessment of pulmonary function in COPD. Seminars in Respiratory and Critical Care Medicine. April 2005. Issue 02. 246-52
6. Pompeyo C Chavez, Navkiran Shokar. Diagnosis and Management of Chronic Obstructive Pulmonary Disease (COPD) in a Primary Care Clinic. COPD: Journal of
Chronic Obstructive Pulmonary Disease. 2009; 6(6), 446-451.
7. Hassan Ghobadi, Saeid Sadeghieh Ahari, Azadeh Kameli, Sharzad M.Lari. The Relationship between COPD Assessment Test (CAT) Scores and Severity of Airflow
Obstruction in Stable COPD Patients. Tanaffos 2012; 11(2): 22-26
8. Kurashima K, Takaku Y, Ohta et al. COPD assessment test and severity of airflow limitation in patients with asthma, COPD, and asthma–COPD overlap syndrome. International Journal of COPD 2016:11 479–487.
9. Jindal SK. COPD: the unrecognized epidemic in India. JAPI 2012; Vol. 60 Suppl., 14–16.
10. Jones PW, Brusselle G, Dal Negro RW et al. Properties of the COPD assessment test in a cross-sectional European study. Eur Respir J. 2011, 38:29-35.
11. You-Hui T, Yan Zhang Y and GuangHe F. Utility of the CAT in the therapy assessment of COPD exacerbations in China. BMC Pulmonary Medicine 2014 14-42.
12. Choudhary Sumer, Abraham Rini, Tayade B, Khan Shafee, Doshi Virag, More Vishal. CAT Score in Chronic Obstructive Pulmonary Disease, Impact on Health: Assessment in Our Region. Panacea Journal of Medical Sciences, January-April, 2016;6(1): 13-19
13. Sundeep Salvi et. al. Prevalence of COPD in a rural population in India. European Respiratory journal. Sept. 2014. vol. 38 no. Suppl 55.
How to Cite
1.
Dr. R. J. Khyalappa, Dr. S. M. Thanekar. CLINICAL UTILITY OF CAT SCORE IN PATIENTS WITH COPD EXACERBATION AND STABLE DISEASE AND ITS CORRELATION WITH PULMONARY FUNCTION TESTS: AN OBSERVATIONAL PROSPECTIVE STUDY. Med. res. chronicles [Internet]. 1 [cited 2024Apr.27];6(1):40-4. Available from: https://medrech.com/index.php/medrech/article/view/365
Section
Original Research Article