Exploring The Unforeseen: Extrapulmonary tuberculosis (EPTB) With Rifampicin Resistance (Rr) In Cornelia De Lange Syndrome (Cdls) – A Rare Revelation
Abstract
Tuberculosis (TB) remains a major global health concern, with extrapulmonary tuberculosis (EPTB) contributing significantly to its burden. This abstract discusses the clinical manifestations, diagnosis, and management of EPTB, focusing on tuberculous lymphadenitis (TBL), the most prevalent form of EPTB. Diagnostic challenges and the importance of molecular diagnostic tools like Xpert MTB/Rif Ultra are highlighted, emphasizing the need for prompt and accurate diagnosis to initiate appropriate treatment. Additionally, the abstract explores the coexistence of Cornelia de Lange syndrome (CdLS), a multisystem disorder, in a patient with EPTB with Rifampicin Resistance (RR), underscoring the complexity of managing multiple medical conditions. The significance of a multidisciplinary approach involving pediatricians, geneticists, and infectious disease specialists is emphasized in providing comprehensive care tailored to the patient's unique needs. Long-term follow-up and supportive care are crucial for optimizing outcomes in complex medical conditions like TBL and CdLS, highlighting the importance of ongoing monitoring and intervention.
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References
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