Comparison of MACE between High and Low TIMI Risk

  • Md. Abdul Mukid Assistant Professor (Cardiology), Parkview Medical College, Sylhet, Bangladesh
  • Md. Shahabuddin Ex: Professor and Departmental Head (Cardiology), MAG Osmani Medical College, Sylhet & Vice Principal and Departmental Head (Cardiology), Parkview Medical College, Sylhet, Bangladesh
  • Farzana Tazin Senior Consultant (Cardiology), Clinical and Intervention Cardiologist, National Heart Foundation Hospital, Sylhet, Bangladesh
  • Md. Suhail Alam Assistant Professor, Department of Cardiology, Jalalabad Ragib Rabeya Medical College, Sylhet, Bangladesh
  • Partha Sarathi Roy Chowdhury Junior Consultant (Cardiology), 250 Bed Adhunic Sadar Hospital, Hobigonj, Bangladesh
Keywords: Comparison, TIMI risk score, STEMI, MACE

Abstract

Introduction: Patients with ST-segment elevation myocardial infarction (STEMI) have increased risk for death and adverse cardiac events. Of great concern is the risk of cardiac arrest that accounts for the majority of early deaths and other major adverse cardiac events. Significant hospital resources are dedicated to these high risk patients.

Objective: To see the correlation of MACE between High and Low TIMI Risk.

Methodology: This cross-sectional prospective study was conducted in the Department of Cardiology, Sylhet MAG Osmani Medical College Hospital, Sylhet during the period from July 2017 to June 2018. Fifty patients with definite diagnosis of acute STEMI, received streptokinase, aged above 18 years and both sex were included. Prior myocardial infarction, coronary revascularization procedures either CABG or angioplasty or coronary stenting; co-morbidities such as renal failure, heart failure, cardiomyopathy, valvular heart disease and congenital heart disease were excluded. On admission TIMI was recorded. In hospital MACE were also recorded.

Results: The mean age of patients was 52.64 (SD 11.88) years and majority of the patients were male (84%) with male to female ratio was 5.25:1. The mean TIMI risk score for STEMI 4.50 (SD 2.38). In hospital major adverse cardiac events (MACE) occurred in 19 (38.0%) cases. TIMI risk score for STEMI was significantly higher in patients with MACE compared to without MACE (16.95, SD 1.78 versus 3.00, SD 1.10; p<0.001) respectively.

Conclusion: In hospital major adverse cardiac events (MACE) occurred in 19 (38.0%) cases. TIMI risk score for STEMI was significantly higher in patients with MACE compared to patients without MACE (16.95, SD 1.78 versus 3.00, SD 1.10; p<0.001) respectively.  From the study we conclude that TIMI risk score (5 or above) is a reliable tool in predicting in- hospital major adverse cardiac events in ST-segment elevation myocardial infarction.

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Author Biographies

Md. Abdul Mukid, Assistant Professor (Cardiology), Parkview Medical College, Sylhet, Bangladesh

 

 

Md. Shahabuddin, Ex: Professor and Departmental Head (Cardiology), MAG Osmani Medical College, Sylhet & Vice Principal and Departmental Head (Cardiology), Parkview Medical College, Sylhet, Bangladesh

 

 

Farzana Tazin, Senior Consultant (Cardiology), Clinical and Intervention Cardiologist, National Heart Foundation Hospital, Sylhet, Bangladesh

 

 

Md. Suhail Alam, Assistant Professor, Department of Cardiology, Jalalabad Ragib Rabeya Medical College, Sylhet, Bangladesh

 

 

Partha Sarathi Roy Chowdhury, Junior Consultant (Cardiology), 250 Bed Adhunic Sadar Hospital, Hobigonj, Bangladesh

 

 

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CITATION
DOI: 10.26838/MEDRECH.2023.10.3.696
Published: 2023-05-16
How to Cite
1.
Mukid MA, Shahabuddin M, Tazin F, Alam MS, Chowdhury PSR. Comparison of MACE between High and Low TIMI Risk. Med. res. chronicles [Internet]. 2023May16 [cited 2024May18];10(3):198-05. Available from: https://medrech.com/index.php/medrech/article/view/676
Section
Original Research Article