• Dr. Gautam Rawal Attending Consultant-Critical Care, Rockland Hospital, Qutab Institutional Area, New Delhi, India
  • Dr. Sankalp Yadav General Duty Medical Officer-II, Chest Clinic Moti Nagar, New Delhi, India
  • Ms. Saifali Nagayach Dietician, Rockland Hospital, Qutab Institutional Area, New Delhi, India
Keywords: Cholesterol, Phytosterols, Sterols


Phytosterols are a family of compounds similar to cholesterol, which have been shown to lower cholesterol levels when supplemented in the diet. A daily dose of 2–3 g of phytosterols has been shown to reduce LDL-cholesterol levels by 5–15%. They can be consumed in the form of phytosterol enriched functional foods or nutraceutical preparations. Increasing the number of phytosterols consumed in a variety of foods may be an important way of reducing cholesterol levels and preventing coronary heart disease.


Download data is not yet available.


1. Katcher H, Hill A, Lanford J, Yoo J, Kris-Etherton P. Lifestyle Approaches and Dietary Strategies to Lower LDL-Cholesterol and Triglycerides and Raise HDL-Cholesterol. Endocrinology and Metabolism Clinics. 2009;36(1).
2. Ferdowsian H, Barnard N. Effects of Plant-Based Diets on Plasma Lipids. The Amer J Cardiol. 2009;104:947-956.
3. Jenkins DJ, Kendall CW, Popovich DG, Vidgen E, Mehling CC, Vuksan V, et al. Effect of a very-high-fiber vegetable, fruit, and nut diet on serum lipids and colonic function. Metabolism. 2001; 50: 494–503.
4. Chen ZY, Jiao R, Ma KY. Cholesterol-lowering nutraceuticals and functional foods. J Agric Food Chem. Review.2008;56(19):8761-73.
5. Anderson JW, Allgood LD, Lawrence A, Altringer LA, Ierdack GR, Hengehold DA. Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: a meta-analysis of 8 controlled trials. Am J Clin Nutr. 2000; 71: 472-479.
6. Woyengo TA, Ramprasath VR, Jones PJH. Anticancer effects of phytosterols. European Journal of Clinical Nutrition. 2009; 63:813–20.
7. Awad A, Fink C. Phytosterols as Anticancer Dietary Components: Evidence and Mechanism of Action. J Ntr. 2000; 130(9):2127-30.
8. Awad AB, Williams H, Fink CS. Effect of phytosterols on cholesterol metabolism and MAP kinase in MDA-MB-231 human breast cancer cells. J Nutr Biochem. 2003; 14(2):111-9.
9. Wasserman SI. Approach to the person with the allergic or immunologic diseases. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 257.
10. Bouic PJ. The Role of Phytosterols and Phytosterolins in Immune Modulation: a review of the past 10 years. Curr Opin Clin Nutr Metab Care. 2001;4(6):471-5.
11. Phillips K M , Ruggio DM , Ashraf-Khorassani M. Phytosterol Composition of Nuts and seeds Commonly Consumed in the United States. Journal of agriculture and food chemistry. 2005; 53 (24): 9436–9445
12. Bravo E, Napolitano M, Lopez-Soldado I, Valeri M, Botham KM, Stefanutti C. Hypercholesterolaemia alters the acids from fish oil. Eur J Clin Invest. 2006;36(11):788-95.
13. Ellegard LH, Andersson SW, Normen AL, Andersson HA. Dietary plant sterols and cholesterol metabolism. Nutr Rev. 2007; 65(1):39-45.
14. Racette SB, Lin X, Lefevre M, Spearie CA, Most MM, Ma L, et al. Dose effects of dietary phytosterols on cholesterol metabolism: a controlled feeding study. Am J Clin Nutr. 2010;91(1):32-8.
15. Kritchevsky D. Phytosterols. Adv Exp Med Biol. 1997; 427: 235-43.
How to Cite
Rawal G, Yadav S, Nagayach S. PHYTOSTEROLS AND THE HEALTH. Med. res. chronicles [Internet]. 2015Jun.10 [cited 2024Feb.23];2(3):441-4. Available from:
Short Communication