TREATMENT OF PERIAPICAL LESION WITH PLATELET-RICH FIBRIN – A BIO-FUEL FOR TISSUE REGENERATION: A CASE REPORT

  • Utpal Kumar Das Professor, HOD, Dept. Conservative Dentistry & Endodontics Guru Nanak Institute of Dental Sciences & Research, Kolkata, West Bengal.
  • Ranu Choudhury Post Graduate Student, Dept. of Conservative Dentistry & Endodontics Guru Nanak Institute of Dental Sciences & Research, Kolkata, West Bengal.
  • Niladri Maiti Senior Lecturer, Dept. Conservative Dentistry & Endodontics Guru Nanak Institute of Dental Sciences & Research, Kolkata, West Bengal.
Keywords: Periapical surgery, Platelet-rich fibrin, Bone regeneration

Abstract

Excogitation in the concept of tissue engineering has brought about a drastic improvement in the healing response of tissues. Wound healing is a staged process that involves the activity of leukocytes and platelets. The growth factors present in platelets are important to guide the regenerating cells to the area of healing. Platelet-rich fibrin is one such material that holds these growth factors enmeshed in the fibrin network resulting in their sustained release over a period of time that can accelerate the wound healing process. Nowadays platelet-rich fibrin is used in various treatment procedures in endodontics. This case report illustrates the use of platelet-rich fibrin in bone regeneration after periapical surgery.

Downloads

Download data is not yet available.

References

1. Torabinejad M, Corr R, Handysides T, Shahrokh S. Outcomes of nonsurgical retreatment and endodontic surgery: A systematic review. J Endod 2009;35:930-7.
2. Prakash S, Thakur A. Platelet concentrates present, past and future. J Maxillofac Oral Surg 2011; 10(1):45-49.
3. Choukroun J, Adda F, Schoffler C, Vervelle A. An opportunity in perio-implantology: the PRF (in French). Implantodontie 2001;42:55-62].
4. Ross R, Glomset J, Kariya B, Harker L. A platelet dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Proc Nati Acad Sci U S A 1074;71:1207-1210]
5. Aichelman-Reidy ME, Myukna RA. Bone replacement grafts. Dent Clin North Am 1998;42:491-503]
6. Dean-HW, Ronald LB, David MG. Platelet Gel – An Autologous Alternative to Fibrin Glue with Applications in Oral and Maxillofacial Surgery. J Oral Max Fac Sur. 1997;55:1294-9.
7. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet – rich plasma. Growth factor enhansment for bone grafts. Oral Surg Oral Med Oral Path Oral Radiol Endod 1998;85:638-46.
8. Singh S, Singh A, Singh R. Application of PRF in the surgical management of periapical lesions. Natl J Maxillofac Surg 2013;4(1):94-99]
9. Megha Agarwal, Vineet Agarwal. Platelet Rich Fibrin and its Application in Dentistry – A Review Artcle. National Journal of Medical and Dental Research. April-June 2014;2:3:51-58]
10. KB Jayalakshmi, S Agarwal et al. “Platelet-Rich fibrin with Beta- Tricalcium Phosphate – A Novel approach of Bone Augmentation in Chronic Periapical lesion: A Case Report. Vol2012, Article ID 902858, 6pages, 2012 doi:10,1155/2012/902858]
11. Malathi K, Muthukumaraswamy A, Beri S. Periodontal regeneration of an intrabony osseous defect with a combination of platelet-rich fibrin abd bovine-derived demineralized bone matrix: A case report. IOSR-JDMS 2013:4(2):20-26]
12. Sujeet V Khiste, Ritam N Tari. Platelet-Rich Fibrin as a Biofuel for Tissue Regeneration: Review Article. Hindawi Publishing Corporation, ISRN Biomaterials Vol 2013, Article ID 627367, 6 pages.
How to Cite
1.
Das UK, choudhury R, Maiti N. TREATMENT OF PERIAPICAL LESION WITH PLATELET-RICH FIBRIN – A BIO-FUEL FOR TISSUE REGENERATION: A CASE REPORT. Med. res. chronicles [Internet]. 2015Aug.10 [cited 2024Nov.25];2(4):534-8. Available from: https://medrech.com/index.php/medrech/article/view/118
Section
Case Report