TREATMENT OF PERIAPICAL LESION WITH PLATELET-RICH FIBRIN – A BIO-FUEL FOR TISSUE REGENERATION: A CASE REPORT
Keywords:
Periapical surgery, Platelet-rich fibrin, Bone regeneration
Abstract
Excogitation in the concept of tissue engineering has brought about a drastic improvement in the healing response of tissues. Wound healing is a staged process that involves the activity of leukocytes and platelets. The growth factors present in platelets are important to guide the regenerating cells to the area of healing. Platelet-rich fibrin is one such material that holds these growth factors enmeshed in the fibrin network resulting in their sustained release over a period of time that can accelerate the wound healing process. Nowadays platelet-rich fibrin is used in various treatment procedures in endodontics. This case report illustrates the use of platelet-rich fibrin in bone regeneration after periapical surgery.
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References
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2. Prakash S, Thakur A. Platelet concentrates present, past and future. J Maxillofac Oral Surg 2011; 10(1):45-49.
3. Choukroun J, Adda F, Schoffler C, Vervelle A. An opportunity in perio-implantology: the PRF (in French). Implantodontie 2001;42:55-62].
4. Ross R, Glomset J, Kariya B, Harker L. A platelet dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro. Proc Nati Acad Sci U S A 1074;71:1207-1210]
5. Aichelman-Reidy ME, Myukna RA. Bone replacement grafts. Dent Clin North Am 1998;42:491-503]
6. Dean-HW, Ronald LB, David MG. Platelet Gel – An Autologous Alternative to Fibrin Glue with Applications in Oral and Maxillofacial Surgery. J Oral Max Fac Sur. 1997;55:1294-9.
7. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet – rich plasma. Growth factor enhansment for bone grafts. Oral Surg Oral Med Oral Path Oral Radiol Endod 1998;85:638-46.
8. Singh S, Singh A, Singh R. Application of PRF in the surgical management of periapical lesions. Natl J Maxillofac Surg 2013;4(1):94-99]
9. Megha Agarwal, Vineet Agarwal. Platelet Rich Fibrin and its Application in Dentistry – A Review Artcle. National Journal of Medical and Dental Research. April-June 2014;2:3:51-58]
10. KB Jayalakshmi, S Agarwal et al. “Platelet-Rich fibrin with Beta- Tricalcium Phosphate – A Novel approach of Bone Augmentation in Chronic Periapical lesion: A Case Report. Vol2012, Article ID 902858, 6pages, 2012 doi:10,1155/2012/902858]
11. Malathi K, Muthukumaraswamy A, Beri S. Periodontal regeneration of an intrabony osseous defect with a combination of platelet-rich fibrin abd bovine-derived demineralized bone matrix: A case report. IOSR-JDMS 2013:4(2):20-26]
12. Sujeet V Khiste, Ritam N Tari. Platelet-Rich Fibrin as a Biofuel for Tissue Regeneration: Review Article. Hindawi Publishing Corporation, ISRN Biomaterials Vol 2013, Article ID 627367, 6 pages.
How to Cite
1.
Das UK, choudhury R, Maiti N. TREATMENT OF PERIAPICAL LESION WITH PLATELET-RICH FIBRIN – A BIO-FUEL FOR TISSUE REGENERATION: A CASE REPORT. Med. res. chronicles [Internet]. 2015Aug.10 [cited 2024May5];2(4):534-8. Available from: https://medrech.com/index.php/medrech/article/view/118
Section
Case Report
