EVALUATION OF CLINICAL EFFICACY OF CISSUS QUADRANGULARIS IN PAIN MANAGEMENT AND BONE HEALING AFTER IMPLANT PLACEMENT – A PILOT STUDY
Abstract
Background: The ancient Ayurveda science of medicine describes various herbal preparations that achieve the hastening of bone healing and relief from pain and swelling.
Aim: To evaluate the clinical efficacy of cissus quadrangularis in pain management and bone healing after implant placement.
Objectives: To evaluate the clinical and biochemical parameters using cissus quadrangularis after implant placement in terms of measurements of pain, swelling, serum alkaline phosphatase level, and bone density around the implant.
Type of Study: Prospective Randomized Control Study.
Materials and Methods: Patients were divided into two groups. Study group and Control group. Three patients in each group received implants either single implants or multiple implants. The study group was given cissus quadrangularis without any additional medicine and the control group was given routine antibiotics (Amoxicillin 500mg and diclofenac sodium). The pain was assessed using VAS at 3rd, 5th day and after one week, the swelling was checked in form of mild, moderate, and severe, and serum alkaline phosphatase was recorded preoperatively and 4th and 8th week of post-operative to evaluate bone healing. Patents’ Orthopantomogram were subjected to densitometric analysis for evaluating the changes in the bone density in both the study and control group.
Results: Pain and swelling were minimal and bone healing was more in the study group and less in the control group. There was an increase in serum alkaline phosphatase levels at different follow-ups in study groups when compared to the control group. Densitometric analysis showed significant improvement in bone density around the implant in the study group when compared to the control group.
Conclusion: The use of cissus quadrangularis after implant placement showed a significant effect on pain and swelling management. Also, rising levels of serum alkaline phosphatase and good bone density when compared to the control group indicated new bone formation thus helps in osteointegration.
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References
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