CRITICAL EVALUATION OF LENS INDUCED GLAUCOM

  • Dr N G Raut HOD and Professor, Dept; Of Ophthalmology, Indira Gandhi Govt; Medical College, Nagpur, India
  • Dr Ravi Chauhan Associate Professor, Dept; Of Ophthalmology, Indira Gandhi Govt; Medical College, Nagpur, India
  • Dr Sandesh Sonarkhan Indira Gandhi Govt; Medical College, Nagpur, India
Keywords: lens induced glaucoma, IOP, complication and management of LIG

Abstract

Purpose: This longitudinal study was to outline the different characteristics of lens induced glaucoma (LIG), to determine the risk factors, to study the intra-operative and post-operative complications and their consequences on post-operative visual acuity & intraocular pressure, following small incision cataract surgery.

Methodology: A total of 50 patients were included in the study. A standardized detailed performa was used and the patient’s data was collected. Based on the clinical findings, etiological diagnosis of lens induced glaucomas was made. Reasons for late presentations were also noted. Appropriate medical management was given followed by surgical intervention (manual small incision cataract surgery). The intra-operative and post-operative complications were noted. Patients were followed up to 6 week postoperatively and clinical findings were noted. All data was analyzed statistically using Chi – square test.
Result:
• Most common subtype of lens induced glaucoma noted was phacomorphic variety (68%) & phacolytic glaucoma (24%).

• Most common Intra – operative complication being Shallow anterior chamber (AC), seen in 9 cases, Posterior capsule rupture with Vitreous loss (PCR with VL) 4 cases. Least common being, cortical remnants in 2 cases due to associated vitreous loss. The intra – operative complication rate was almost equal in all groups except shallowing of anterior chamber which was more common in cases of phacomorphic glaucoma.

• Post – operatively corneal oedema with striate keratopathy and iritis were noted in 10 cases (20%) each. Incidence of post – operative complication of corneal oedema with striate keratopathy was more in phacomorphic group while post – operative iritis was more in phacolytic group.

• All cases of lens particle glaucoma and glaucoma associated with subluxation / dislocation of lens, had post – operative complications of corneal oedema with striate keratopathy and iritis both.

• Good visual acuity (6/6 - 6/12) achieved in cases which presented within 1 week (83.33%) , whereas poor visual acuity of less than 6/60 was more in cases which presented beyond 2 weeks (25%) In this study, duration of symptoms had a linear relation with best-corrected visual acuity at final follow up. More the delay in presentation, poorer was the visual outcome, which was both clinically and statistically significant (p=0.001).

• Clinically, significant proportion of cases with IOP at presentation less than 40 mmHg (79.16%) achieved good visual acuity (6/6-6/12), than cases with IOP more than 40 mm Hg (42.30%). This was found to be statistically significant as well with p value = < 0.002. Whereas, no significant difference was found for poor visual outcome (<6/60). The IOP at last follow up was reduced to normal limits (14.73 ± 2.63 mm Hg). It was found that the IOP tends to be higher with the delay in presentation beyond 2 weeks.

Conclusion: There is no inclination found towards age, sex, religion. Phacomorphic glaucoma was the most common entity. Visual outcome is directly related with height of IOP and duration of raised IOP preoperatively. Early detection, medical and surgical intervention yields better visual outcome. Health education and awareness regarding cataract surgery will definitely decrease the incidence of LIG.

Downloads

Download data is not yet available.

References

1. Thylefors B, Négrel AD, Pararajasegaram R, Dadzie KY. Global data on blindness. Bull World Health Organ. 1995; 73:115–21.
2. Murthy GV, Gupta SK, Bachani D, Jose R, John N. Current estimates of blindness in India. Br J Ophthalmol. 2005; 89:257–60.
3. Thulasiraj RD, Nirmalan PK, Ramakrishnan R, Krishnadas R, Manimekalai TK, Baburajan NP, et al. Blindness and vision impairment in a rural south Indian population: The Aravind Comprehensive Eye Survey. Ophthalmology. 2003;110:1491–8.
4. Thulasiraj RD, Rahamathulla R, Saraswati A, Selvaraj S, Ellwein LB. The Sivaganga eye survey: Blindness and cataract surgery. Ophthalmic Epidemiol. 2002; 9:299–312.
5. Nirmalan PK, Thulasiraj RD, Maneksha V, Rahmathullah R, Ramakrishnan R, Padmavathi A, et al. A population based eye survey of older adults in Tirunelveli district of south India: Blindness, cataract surgery and visual outcomes. Br J Ophthalmol. 2002 86:505–12.
6. Sharma RG, Verma GL, Singhal B. A clinical evaluation of Scheie's operation with sclerectomy along with lens extraction in lens induced glaucoma. Indian journal of ophthalmology. 1983; 31(5):639-41.
7. Jain IS, Gupta A, Dogra M R, Gangwar D N, Dhir S P. Phacomorphic glaucoma Management and visual prognosis. Indian J Ophthalmol 1983;31(5):648-53.
8. Fletcher AE, Donoghue M, Devavaram J, et al. Low Uptake of Eye Services in Rural India: A Challenge for Programs of Blindness Prevention. Arch Ophthalmol.1999;117(10):1393-99.
9. Epstein DL. Lens induced open angle glaucoma. In R Ritch & MB Shields editors. The secondary glaucomas. St.Louis: CV Mosby; 1982. pp. 121-130.
10. Murphy GE. Acute phacolytic glaucoma with primary intraocular lens implantation after intracapsular cataract extraction. J Am Intraocular Implant Soc. J.1981; 7(3):266-67.
11. Lazar M, Bracha R, Nemet P. Cataract extraction during acute attack of phacolytic glaucoma. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1976;
81(1):183-84.
12. Irvine SR. Lens induced uveitis and glaucoma. In: Haik GM, editors. Symposium of the lens: Transaction of the New Orleans Academy of Ophthalmology. St. Louis: CV Mosby; 1957. Pp.186-99.
13. Gross KA, Pearce JL. Phacolytic glaucoma with ECCE and Primary IOL implantation. Cataract. 1984; 11(2):22-23.
14. Venkatesh R, Tan CS, Kumar TT, Ravindran RD. Safety and efficacy of manual small incision cataract surgery for phacolytic glaucoma. Br J Ophthalmol. 2007;
91(3): 279-81.
15. Lane SS, Kopietz LA, Lindquist TD, Leavenworth N. Treatment of phacolytic glaucoma with extracapsular cataract extraction. Ophthalmology. 1988; 95(6):749-
53.
16. Singh G, Kaur J, Mall S. Phacolytic glaucoma - Its treatment by planned extracapsular cataract extraction with posterior chamber intraocular lens implantations. Indian J Ophthalmol. 1994; 42(3):145–47.
17. Gifford H. Danger of the spontaneous cure of senile cataracts. Am J Ophthalmol. 1900; 17:289–93.
18. Zeeman WPC. Zwei Falle von Glaucoma phacogeneticum mitanatomischem Befund. Ophthalmologica. 1943; 106(3):136–42.
19. Irvine SR, Irvine AR Jr. Lensinduced uveitis and glaucoma. PartIII. "Photogenetic glaucoma": Lensinduced glaucoma; mature or hypermature cataract; Open irido corneal angle. Am J Ophthalmol.1952; 35(3):489–99.
20. Flocks M, Littwin CS, Zimmerman LE. Phacolytic glaucoma: a clinicopathologic study of one hundred thirty-eight cases of glaucoma associated with
hypermature cataract. Arch Ophthalmol. 1955; 54(1):37–45.
21. McMahon MS, Weiss JS, Riedel KG, Albert DM: Clinically unsuspected phacoanaphylaxis after extracapsular cataract extraction with intraocular lens implantation. Br J Ophthalmol. 1985; 69(11):836–40.
22. Epstein DL, Jedziniak JA, Grant WM. Obstruction of aqueous outflow by lens particles and by heavy-molecular weight soluble lens proteins. Invest Ophthalmol Vis Sci. 1978; 17(3):272–7.
23. Epstein DL, Jedziniak JA, Grant WM. Identification of heavymolecular weight soluble proteins in aqueous humour in human phacolytic glaucoma. Invest
Ophthalmol Vis Sci. 1978;17(5):398–402.
24. Epstein DL. Diagnosis and management of lens induced glaucoma. Ophthalmology.1982; 89(3):227-30.
25. Rao SK, Padmanabhan P. Capsulorhexis in eyes with phacomorphic glaucoma. J Cataract Refract Surg.2000;26(4):447-48.
26. Tomey KF, Al-Rajhi AA. Neodymium: YAG laser iridotomy in the initial management of phacomorphic glaucoma. Ophthalmology. 1992; 99(5):660-65.
27. Mueller H. Phacolytic glaucoma and Phacogenic Ophthalmia (lens induced uveitis). Trans Ophthalmol Soc U K. 1963; 83:689–704.
28. Verhoeff FH, Lemoine AN. Endophthalmitis phacoanaphylactica. In: Transactions of the international congress of ophthalmologists. Washington DC: William F Fell;1922. p. 234-37.
29. Rahi AH, Mishra RN, Morgan G. Immunopathology of the lens. III. Humoral and cellular immune responses to autologous lens antigen and their roles in ocular
inflammation. Br J Ophthalmol. 1977; 61(6):371–79.
30. Chandler PA. Choice of Treatment in Dislocation of the Lens: The First E. B. Dunphy Lecture. Arch Ophthalmol. 1964; 71(6):765-786.
31. Jarrett WH. Dislocation of the Lens: A study of 166 Hospitalized cases. Arch Ophthalmol. 1967; 78(3):289-296.
32. Luebbers JA, Goldberg MF, Herbst R, et al. Iris transillumination and variable expression in ectopia lentis et pupillae. Am J Ophthalmol. 1977; 83(5):647–56.
33. Nelson LB, Maumenee IH. Ectopia lentis. Surv Ophthalmol. 1982; 27(3):143-60.
How to Cite
1.
Dr N G Raut, Dr Ravi Chauhan, Dr Sandesh Sonarkhan. CRITICAL EVALUATION OF LENS INDUCED GLAUCOM. Med. res. chronicles [Internet]. 1 [cited 2024Nov.6];3(1):139-45. Available from: https://medrech.com/index.php/medrech/article/view/155
Section
Original Research Article