HYPERTENSIVE DISORDERS OF PREGNANCY AND ASSOCIATED FACTORS AMONG ADMITTED PREGNANT CASES IN DESSIE TOWN REFERRAL HOSPITAL, NORTH EAST ETHIOPIA, 2015
Introduction: Hypertensive disorder of pregnancy (HDP) is the most common medical problem encountered during pregnancy, which increased risk of maternal and neonatal mortality and morbidity. Despite of its significant effect, the magnitude and risk factors yet not assessed at local context.
Objective: To assess the occurrence of hypertensive disorders of pregnancy and associated factors among admitted pregnant women in obstetrics and gynecology ward in Dessie referral hospital, North East Ethiopia.
Methods: Institutional based retrospective cross sectional study in 320 admitted pregnant cases at obstetrics and gynecologic ward through one year document review and documents selected with systematic random sampling. Bivariate and multivariate logistic regression were used to identify significant risk factors for the development of hypertension disorder of pregnancy and presented by AOR and P-value.
Result: Out of 320 sample pregnant mothers, 28(8.8%) had confirmed hypertensive disorders of pregnancy (HDP). Of which 13(46.4%) were mild preeclampsia, 8(28.6%) were severe preeclampsia, 3(10.7%) were eclampsia, 4(14.2%) were gestational hypertension. Being urban residence (OR=4.409, 95%CI ;( 1.459-13.324)), nully parity (OR=11.363, 95%CI ;( 3.991-32.349)) and multiple pregnancy (OR=3.369, 95CI ;( 1.178-59.442)) were statically significant risk factors for occurrence hypertension disorder of pregnancy. Regarding past medical conditions, having pre - existing hypertension, renal disease and cardiac disease were positively associated risk factors for the development of HDP.
Conclusion: Significant numbers of pregnant mothers develop hypertensive disorder of pregnancy. To decrease this burden, health personnel’s should work extensively at static and community level in reducing risk factors which lead to hypertension disorder of pregnancy.
2. FMOH. Management Protocol on selected obstetric topics. Addis Ababa Ethiopia, 2010
3. Karen L. Jean-Marie M, Llana S. Diagnosis, Evaluation, and Management of the Hypertensive Disorders of Pregnancy. SOGC Clinical practice guide line. 2014: 307
4. Bergstrom S. Pre-eclampsia and Eclampsia. In: Lawson JB, Harrison KA, Bergstrom S. eds. Maternity Care in Developing Countries. London. RCOG Press.2001; 146-159
5. Carroli G, Rooney C, Villa I. ‘‘how effective is Antenatal Care in preventing maternal mortality and serious morbidity? An overview of evidence’’. Pediatric Perinatal. Epidemiology 2001;15(1): 13-20
6. World Health Organization. Millennium Development Goal for lancet 12. April 2010.
7. Central Statistical Agency. Ethiopia Demographic and Health Survey 2011. Addis Ababa, Ethiopia; March 2012.
8. Hutcheon JA, Lisonkova S, Joseph KS. Epidemiology of pre-eclampsia and the other hypertensive disorders of pregnancy. PubMed, Best Pract Res ClinObstetGynaecol. 2011, 25:391, 403.
9. Mekbeb T, Ketsela K. Preeclampsia/eclampsia at Yekatit 12 Hospital, Addis Ababa, Ethiopia. East Afr Med J. 1991, 68(11):893–899
10. Wagner, S.J., Barac, S. and Garovic, V.D. Hypertensive Pregnancy Disorders current Concepts. Journal of Clinical Hypertension. 2007, 9:560-566. Available at
11. Henry, C.S., Biedermann, S.A., Campbell, M.F. and Guntupalli, J.S. Spectrum of Hypertensive Emergencies in Pregnancy. Critical Care Clinics. 2004, 20: 697-712. Available at http://dx.doi.org/10.1016/j.ccc.2004.05.014
12. Christine L , Charles S, Jonathan M, Jane B, David J. Hypertensive disorders in pregnancy. MJA. April 2005: 82: 7
13. Shahla K, Soheila, Lotfi M, Mohammad A. Study of the Prevalence of Hypertension and Complications of Hypertensive Disorders in Pregnancy. Open Journal of Preventive Medicine. 2014: 4: 860-867
14. Manjusha S, Vandana N, Ronak S, Atmaram P. Incidence of pregnancy induced hypertension and prescription pattern of antihypertensive drugs in pregnancy. International Journal of Pharma Sciences and Research (IJPSR. April 2014:: 5 :4
15. Prakash J, Pandey LK, Singh AK, Kar B. Hypertension in pregnancy: Hospital based study. J Assoc Physicians of India. 2006: 54:273–278
16. Khawajan P. Paraveen A. Hussen U. Zahid B. Rehman R. Frequency and Obstetric Outcome of Hypertensive Disorders of Pregnancy Medical College/Sir Ganga Ram Hospital, Lahore. 2004
17. Wolde Z. Segni H. and Woldie M (2011). Hypertensive Disorders of Pregnancy in Jimma University Specialized Hospital. Ethiop J Health Sci. Nov 2011: 21(3).
18. Teklu S, Gaym A. Prevalence and clinical correlates of the hypertensive disorders of pregnancy at Tikur Anbessa Hospital, Addis Ababa, Ethiopia. Ethiop. Med J. Jan. 2006. 44(1):17–26
19. Zibaeenezhad M, Ghodsi M, Arab P, Gholzom N. The Prevalence of Hypertensive Disorders of Pregnancy in Shiraz, Southern Iran. Iranian Cardiovascular Research Journal. 2010: 4:.4.
20. Kirsten D, Deborah H, Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies. BMJ. March 2005: 10: 1136
21. Myles W, Anand S, Ricardo J, Jenny S, Jeffrey L, Ravi T. Differential Risk of Hypertensive Disorders of Pregnancy among Hispanic Women. Journal of American society Nepharology. February 26, 2004: Available from: http://jasn.asnjournals.org/content/15/5/1330.full#ref-22
22. Kumar S, Unnikrishnan B, Nagaraj K and S Jayaram K. Determinants of Pre-eclampsia: A Case–control Study in a District Hospital in South India. Indian
J Community Med. 2010: 35(4): 502–505.
23. Corrie M, Kate T, Abigail F, Scott M, Debbie A. Gestational weight gain as a risk factor for hypertensive disorders of pregnancy. America journal of obstetric
and gynecology,AJOG. October 2013: 209(4):327