QUANTITATIVE DIAGNOSIS OF BRAIN TUMORS USING MAGNETIC RESONANCE SPECTROSCOPY RELATIVE TO ANALOGUE IMAGES
Abstract
The aim of this work was to determine the diagnostic variations between magnetic resonance spectroscope MRS and the conventional magnetic resonance imaging (MRI) analog image i.e. the accuracy and sensitivity of MRS, MRI and CT relative to histological section. The adapted method was a retrospective study for collecting data of brain tumor patients (350) which were being analyzed using Excel software. The results showed that: brain tumors represent an incident of 54% in Sudan during 2014 – 2017 with an increasing factor of 7.2/year. MRS showed excellent diagnostic achievement relative to standard (histology) with accuracy, sensitivity, and specificity as 93%, 90% and 85% respectively, the Diagnosis of analogue MRI by different radiologist showed 91%, 83% and 76% for accuracy, sensitivity, and specificity respectively; while CT showed 80%, 75% and 15% for accuracy, sensitivity and specificity respectively. MRS usually surpass MRI compared with the standard (histology) and the T-test showed a significant point of 0.5, depending on the level of Choline (Cho), N-Acetyl-Aspartate (NAA), Creatine/ Phosphocreatine (Cr) and Lactate (Lac).
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