NEONATAL MALARIA
Keywords:
Neonatal Malaria, Congenital malaria, Plasmodium falciparum, Plasmodium vivax, Chloroquine, Antimalarial
Abstract
Neonatal malaria, once considered a rare diagnosis is frequently being diagnosed in Neonatal Intensive Care Units in infants admitted with suspected neonatal sepsis, particularly in highly endemic regions. Most infections are caused by Plasmodium falciparum, and Plasmodium vivax. The signs and symptoms are indistinguishable from neonatal septicemia, requiring a high index of suspicion for its diagnosis. Blood smear examination remains the gold standard; however several rapid diagnostic tests are now available, particularly for diagnosing Plasmodium falciparum infection. Chloroquine remains the drug of choice for treating congenital malaria, other antimalarials have been used with success in treating chloroquine-resistant neonatal malaria.
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References
1. Olanrewaju WI. Malaria in the neonate: Report of two cases. West Afr J Med 1999;18:139-40.
2. De Silva DH, Mendis KN, Premaratne UN, Jayatilleke SM, Soyza PE: Congenital malaria due to Plasmodium vivax: a case report from Sri Lanka. Trans R Soc Trop Med Hyg 1982, 76:33-35.
3. Ojukwu JU, Ezeonu CT, Ogbu CN. Severe Malaria in Neonates Masquerading as Septicemia. Nigerian Journal of Paediatrics 2004; Vol.31(2):48-55
4. Lt Col Vidyashankar C, Lt Col Choudhary RK, Lt Col (Ms) Das Shobana. Neonatal Malaria: Report of Two Cases. MJAFI 2003; 59: 358-359
5. Lee WW, Singh M, Tan CL: A recent case of congenital malaria in Singapore.Singapore Med J 1996, 37:541-543
6. Lesko CR, Arguin PM, Newman RDCongenital malaria in the United States: a review of cases from 1966 to 2005.Arch Pediatr Adolesc Med. 2007 Nov;161(11):1062-7.
7. A D Ekanem, M U Anah, J J Udo. The prevalence of congenital malaria among neonates with suspected sepsis in Calabar, Nigeria: Trop Doct 2008;38:73-76
8. Choudhury SP, Dabi DR, Singh RN, Theraja SL Malaria in the newborn. Indian Pediatr. 1983; 20: 41– 43.
9. Thapa BR, Narang A, Bhakoo ON. Neonatal Malaria: a Clinical Study of Congenital and Transfusional Malaria: Journal of Tropical Pediatrics 1987 33(5):266-268
10. Pontual DL, Poilane I, Ledeur F, et al. Report of a case of congenital malaria Plasmodium malariae in France. J Trop Pediatr. 2006 Dec;52(6):448-50
11. Vijayakumar E, Shaheed MM, Katugampola MS, Haque KN. Transfusional malaria in newborn infants: report of two cases. AnnSaudi Med 1990;10:569-72.
12. Ibhansebhor SE. Clinical characteristics of neonatal malaria.J Trop Pediatr 1995;41:330-2.
13. Diallo P, Keita N, Barry I, Conde NM, Diallo PM, Sylla A, Lamah OO, Camin AM, Guiguen C,Senacal J. Malaria in infants in a rural area of maritime Guinea (Guinea Conakry)- Development of antimalarial antibodies and malaria during the first year of life. Bull Soc Pathol Exot. 1998;91(4):291-96
14. Valecha N, Bhatia S, Mehta S, Biswas S, Dash AP: Congenital malaria with atypical presentation: a case report from low transmission area in India. Malar J. 2007 Apr 13;6:43.
15. M. Y. Mukhtar, F. E. A. Lesi, E. U. Iroha, M. T. C. Egri-Okwaji and A. G. Mafe Congenital Malaria Among Inborn Babies at a Tertiary Centre in Lagos, Nigeria Journal of Tropical Pediatrics 2006 52(1):19-23
16. Al Arishi HM, AL Hifzi IS, Ishag Y. Chloroquine-resistant Plasmodium falciparum malaria in an extremely premature infant. Annals of Saudi Medicine 1999;19:245-7.
17. Patwari A, Aneja S, Berry AM, Ghosh S. Neonatal Malaria – A clinical– hematological profile. Indian Pediatr. 1985, 15 (10): 847.
18. Singh T. Neonatal Malaria, Indian Pediatr 1985, 22: 785–786.
19. Singh N, Saxena A, Shrivastava R: Placental Plasmodium vivax infection and congenital malaria in central India. Ann Trop Med Parasitol 2003,97(8):875-8.
20. Neelaiah Siddaraju, Neeta Khurana. Considering the diagnosis of malaria in infants presenting with non-specific symptoms in malaria-endemic areas: case report and review. Case Rep Clin Pract Rev, 2005; 6: 323-326
21. Sotimehin SA, Runsewe-Abiodun TI, Oladapo OT, Njokanma OF, Olanrewaju DM. Performance of a rapid antigen test for the diagnosis of congenital malaria.Ann Trop Paediatr. 2007 Dec;27(4):297-301
22. World Health Organization. Assesment of therapeutic efficacy of antimalarial drugs for uncomplicated falciparum malaria in areas with intense transmission. WHO/MAL96.1077. Geneva, World Health Organization, 1996; p33.
23. Bruce Chwatt LJ. Chemotherapy of Malaria. WHO Technical Report Series No. 27, Geneva, World Health Organization, Geneva 1986.
24. Catherine O Falade, Bidemi O Yusuf, Francis F Fadero, Olugbenga A Mokuolu, Davidson H Hamer, Lateef A Salako. Intermittent preventive treatment with sulphadoxine-pyrimethamine is effective in preventing maternal and placental malaria in Ibadan, Southwestern Nigeria: Malar J. 2007; 6: 88.
25. Khichi QK, Channar MS, Wairraich MI, Butt A. Chloroquine-resistant malaria in neonates. J Coll Physicians Surg Pak. 2005 Jan;15 (1):34-6.
2. De Silva DH, Mendis KN, Premaratne UN, Jayatilleke SM, Soyza PE: Congenital malaria due to Plasmodium vivax: a case report from Sri Lanka. Trans R Soc Trop Med Hyg 1982, 76:33-35.
3. Ojukwu JU, Ezeonu CT, Ogbu CN. Severe Malaria in Neonates Masquerading as Septicemia. Nigerian Journal of Paediatrics 2004; Vol.31(2):48-55
4. Lt Col Vidyashankar C, Lt Col Choudhary RK, Lt Col (Ms) Das Shobana. Neonatal Malaria: Report of Two Cases. MJAFI 2003; 59: 358-359
5. Lee WW, Singh M, Tan CL: A recent case of congenital malaria in Singapore.Singapore Med J 1996, 37:541-543
6. Lesko CR, Arguin PM, Newman RDCongenital malaria in the United States: a review of cases from 1966 to 2005.Arch Pediatr Adolesc Med. 2007 Nov;161(11):1062-7.
7. A D Ekanem, M U Anah, J J Udo. The prevalence of congenital malaria among neonates with suspected sepsis in Calabar, Nigeria: Trop Doct 2008;38:73-76
8. Choudhury SP, Dabi DR, Singh RN, Theraja SL Malaria in the newborn. Indian Pediatr. 1983; 20: 41– 43.
9. Thapa BR, Narang A, Bhakoo ON. Neonatal Malaria: a Clinical Study of Congenital and Transfusional Malaria: Journal of Tropical Pediatrics 1987 33(5):266-268
10. Pontual DL, Poilane I, Ledeur F, et al. Report of a case of congenital malaria Plasmodium malariae in France. J Trop Pediatr. 2006 Dec;52(6):448-50
11. Vijayakumar E, Shaheed MM, Katugampola MS, Haque KN. Transfusional malaria in newborn infants: report of two cases. AnnSaudi Med 1990;10:569-72.
12. Ibhansebhor SE. Clinical characteristics of neonatal malaria.J Trop Pediatr 1995;41:330-2.
13. Diallo P, Keita N, Barry I, Conde NM, Diallo PM, Sylla A, Lamah OO, Camin AM, Guiguen C,Senacal J. Malaria in infants in a rural area of maritime Guinea (Guinea Conakry)- Development of antimalarial antibodies and malaria during the first year of life. Bull Soc Pathol Exot. 1998;91(4):291-96
14. Valecha N, Bhatia S, Mehta S, Biswas S, Dash AP: Congenital malaria with atypical presentation: a case report from low transmission area in India. Malar J. 2007 Apr 13;6:43.
15. M. Y. Mukhtar, F. E. A. Lesi, E. U. Iroha, M. T. C. Egri-Okwaji and A. G. Mafe Congenital Malaria Among Inborn Babies at a Tertiary Centre in Lagos, Nigeria Journal of Tropical Pediatrics 2006 52(1):19-23
16. Al Arishi HM, AL Hifzi IS, Ishag Y. Chloroquine-resistant Plasmodium falciparum malaria in an extremely premature infant. Annals of Saudi Medicine 1999;19:245-7.
17. Patwari A, Aneja S, Berry AM, Ghosh S. Neonatal Malaria – A clinical– hematological profile. Indian Pediatr. 1985, 15 (10): 847.
18. Singh T. Neonatal Malaria, Indian Pediatr 1985, 22: 785–786.
19. Singh N, Saxena A, Shrivastava R: Placental Plasmodium vivax infection and congenital malaria in central India. Ann Trop Med Parasitol 2003,97(8):875-8.
20. Neelaiah Siddaraju, Neeta Khurana. Considering the diagnosis of malaria in infants presenting with non-specific symptoms in malaria-endemic areas: case report and review. Case Rep Clin Pract Rev, 2005; 6: 323-326
21. Sotimehin SA, Runsewe-Abiodun TI, Oladapo OT, Njokanma OF, Olanrewaju DM. Performance of a rapid antigen test for the diagnosis of congenital malaria.Ann Trop Paediatr. 2007 Dec;27(4):297-301
22. World Health Organization. Assesment of therapeutic efficacy of antimalarial drugs for uncomplicated falciparum malaria in areas with intense transmission. WHO/MAL96.1077. Geneva, World Health Organization, 1996; p33.
23. Bruce Chwatt LJ. Chemotherapy of Malaria. WHO Technical Report Series No. 27, Geneva, World Health Organization, Geneva 1986.
24. Catherine O Falade, Bidemi O Yusuf, Francis F Fadero, Olugbenga A Mokuolu, Davidson H Hamer, Lateef A Salako. Intermittent preventive treatment with sulphadoxine-pyrimethamine is effective in preventing maternal and placental malaria in Ibadan, Southwestern Nigeria: Malar J. 2007; 6: 88.
25. Khichi QK, Channar MS, Wairraich MI, Butt A. Chloroquine-resistant malaria in neonates. J Coll Physicians Surg Pak. 2005 Jan;15 (1):34-6.
How to Cite
1.
Dr Manish Kumar. NEONATAL MALARIA. Med. res. chronicles [Internet]. 2017Dec.31 [cited 2024May4];4(06):600-6. Available from: https://medrech.com/index.php/medrech/article/view/282
Section
Review Article
