METFORMIN INDUCED LACTIC ACIDOSIS AND ACUTE RENAL FAILURE
Keywords:
metformin, lactic acidosis, acute renal failure, intoxication
Abstract
Metformin is a biguanide agent and oral antihyperglycemic agent used in the treatment of type 2 diabetes mellitus. Metformin-associated lactic acidosis and acute renal failure is a very rare but life-threatening side effect of metformin. We present the case of a nondiabetic 41 years old woman, who attempted to commit suicide by ingesting more than 20 grams of metformin. She presented with lactic acidosis and acute renal failure to the emergency department. She was successfully treated by hemodialysis. The main treatment method is hemodialysis who presents with lactic acidosis and acute renal failure in metformin intoxication.
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References
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J Emerg Med 2009;16:11–13.
2. Bailey CJ, Turner RC. Metformin. N Eng J Med. 1996; 334:574–579
3. Von Mach MA, Sauer O, Sacha WL. Experiences of a poison center with metformin-associated lactic acidosis. Exp Clin Endocrinol Diabetes 2004;112:187–190.
4. Chang CT, Chen YC, Fang JT, Huang CC. Metformin-associated lactic acidosis: case reports and literature review. J Nephrol 2002; 15:398–402.
5. Turkcuer I, Erdur B, Sari I, Yuksel A, Tura P, and Yuksel S. Severe metformin intoxication treated with prolonged hemodialyses and plasma exchange. Eur
J Emerg Med 2009;16:11–13.
How to Cite
1.
Melda Çelik, Betül Çavuşoğlu Türker, Süleyman Ahbab, Atay Can Kula, Hayriye Esra Ataoğlu. METFORMIN INDUCED LACTIC ACIDOSIS AND ACUTE RENAL FAILURE. Med. res. chronicles [Internet]. 1 [cited 2024Dec.22];5(01):43-5. Available from: https://medrech.com/index.php/medrech/article/view/287
Section
Case Report