ASSESSMENT OF LEFT VENTRICULAR FUNCTIONS BY ECHOCARDIOGRAPHY TO STUDY THE EFFECTS OF 8-12 WEEKS OF TREATMENT IN THYROID PATIENTS
Keywords:
Left Ventricular function test, Echocardiography, systolic and diastolic function test
Abstract
Thyroid disease diagnosed by an imbalance of thyroid hormones. Increased levels cause hyperthyroidism whereas decreased levels cause hypothyroidism. Both conditions have profound cardiovascular manifestations. Left Ventricular (LV) dysfunction can be demonstrated by various echocardiography measurements and can explain such abnormalities with thyroid disease. The present study was planned to assess the effects hyper and hypothyroidism on LV dysfunction. Also the effect of thyroxine replacement and antithyroid therapy for 8-12 weeks, on LV abnormalities of hypothyroidism and hyperthyroidism respectively; were studied. Patients with hypothyroidism were reported with decreased E/A ratio which is significantly improved by thyroxine replacement therapy for 8-12 weeks.
Downloads
Download data is not yet available.
References
1. Fadel BM, Ellahham S, Ringel MD, Lindsay J, Wartofsky L, Burman KD. Hyperthyroid heart disease. Clin Cardiol. 2000;23(6):402-408. doi:10.1002/clc.4960230605
2. Jabbar A, Pingitore A, Pearce SHS, Zaman A, Iervasi G, Razvi S. Thyroid hormones and cardiovascular disease. Nat Rev Cardiol. 2016;14(1):39-55. doi:10.1038/nrcardio.2016.174
3. Klein I, Danzi S. Thyroid disease and the heart. Circulation. 2007;116(15):1725-1735. doi:10.1161/CIRCULATIONAHA.106.678326
4. Cooper DS. Antithyroid drugs. N Engl J Med. 2005;352(9):905-917. doi:10.1056/NEJMra042972
5. State Government Victoria. Thyroid - hypothyroidism. Better Health Channel. http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Thyroid_disorders_hypothyroidism. Published 2013.
6. Grais IM, Sowers JR. Thyroid and the heart. Am J Med. 2014;127(8):691-698. doi:10.1016/j.amjmed.2014.03.009
7. Escobar-Morreale HF, BotellaCarretero JI, Gómez-Bueno M, Galán JM, Barrios V, Sancho J. Thyroid hormone replacement therapy in primary hypothyroidism: A randomized trial comparing L-thyroxine plus liothyronine with L-thyroxine alone. Ann Intern Med. 2005;142(6). doi:142/6/412 [pii]
8. Nagueh SF, Appleton CP, Gillebert TC, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. J Am Soc Echocardiogr. 2009;22:107-133. doi:10.1016/j.echo.2008.11.023
9. Guglielmini C, Rocconi F, Brugnola L, Valerio F, Mattei L, Boari A. Echocardiographic and Doppler echocardiographic findings in 11 wolves (Canis lupus). Vet Rec. 2006;158(4):125-129. doi:10.1136/vr.158.4.125
10. Anderson B. Echocardiography: The Normal Examination and Echocardiographic Measurements. Blackwell Publ. 2000:0. http://books.google.combooks?id=E_S8RI1Hf5IC&printsec=frontcover.
11. Sahn DJ, DeMaria A, Kisslo J, Weyman A. Recommendations regarding quantitation in M-mode echocardiography: Results of a survey of echocardiographic
measurements. Circulation. 1978;58(6):1072-1083. doi:10.1161/01.CIR.58.6.1072
12. Vasan RS, Levy D, Larson MG, Benjamin EJ. Interpretation of echocardiographic measurements: A call for standardization. Am Heart J. 2000;139(3):412-422. doi:10.1016/S0002-8703(00)90084-X
13. Poelaert J, Declerck C, Vogelaers D, Colardyn F, Visser CA. Left ventricular systolic and diastolic function in septic shock. Intensive Care Med. 1997;23(5):553-560. doi:10.1007/s001340050372
14. Nakamura A, Rokosh DG, Paccanaro M, et al. LV systolic performance improves with development of hypertrophy after transverse aortic constriction in mice. Am J Physiol Hear Circ Physiol. 2001;281(3):H1104-12.
15. Dokainish H. Left ventricular diastolic function and dysfunction: Central role of echocardiography. Glob Cardiol Sci Pract. 2015;2015:3. doi:10.5339/gcsp.2015.3
16. Stewart KC, Kumar R, Charonko JJ, Ohara T, Vlachos PP, Little WC. Evaluation of LV diastolic function from color M-mode echocardiography. JACC Cardiovasc
Imaging. 2011;4(1):37-46. doi:10.1016/j.jcmg.2010.09.020
17. Bierig SM, Hill J. Echocardiographic evaluation of diastolic function. J Diagnostic Med Sonogr. 2011;27(2):65-78. doi:10.1177/8756479311401914
18. Dr. Manish K. Bansal, Dr. Prashant Prakash, Dr. Prabhat K. Agrawal, Dr. Varun Gupta, Assessment of Left Ventricular Systolic/Diastolic Function By Echocardiography In Seropositive HIV Otherwise Asymptomatic Patients. Med Res Chron Med Res Chronicles. 2014;1(2):221-227.
2. Jabbar A, Pingitore A, Pearce SHS, Zaman A, Iervasi G, Razvi S. Thyroid hormones and cardiovascular disease. Nat Rev Cardiol. 2016;14(1):39-55. doi:10.1038/nrcardio.2016.174
3. Klein I, Danzi S. Thyroid disease and the heart. Circulation. 2007;116(15):1725-1735. doi:10.1161/CIRCULATIONAHA.106.678326
4. Cooper DS. Antithyroid drugs. N Engl J Med. 2005;352(9):905-917. doi:10.1056/NEJMra042972
5. State Government Victoria. Thyroid - hypothyroidism. Better Health Channel. http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Thyroid_disorders_hypothyroidism. Published 2013.
6. Grais IM, Sowers JR. Thyroid and the heart. Am J Med. 2014;127(8):691-698. doi:10.1016/j.amjmed.2014.03.009
7. Escobar-Morreale HF, BotellaCarretero JI, Gómez-Bueno M, Galán JM, Barrios V, Sancho J. Thyroid hormone replacement therapy in primary hypothyroidism: A randomized trial comparing L-thyroxine plus liothyronine with L-thyroxine alone. Ann Intern Med. 2005;142(6). doi:142/6/412 [pii]
8. Nagueh SF, Appleton CP, Gillebert TC, et al. Recommendations for the evaluation of left ventricular diastolic function by echocardiography. J Am Soc Echocardiogr. 2009;22:107-133. doi:10.1016/j.echo.2008.11.023
9. Guglielmini C, Rocconi F, Brugnola L, Valerio F, Mattei L, Boari A. Echocardiographic and Doppler echocardiographic findings in 11 wolves (Canis lupus). Vet Rec. 2006;158(4):125-129. doi:10.1136/vr.158.4.125
10. Anderson B. Echocardiography: The Normal Examination and Echocardiographic Measurements. Blackwell Publ. 2000:0. http://books.google.combooks?id=E_S8RI1Hf5IC&printsec=frontcover.
11. Sahn DJ, DeMaria A, Kisslo J, Weyman A. Recommendations regarding quantitation in M-mode echocardiography: Results of a survey of echocardiographic
measurements. Circulation. 1978;58(6):1072-1083. doi:10.1161/01.CIR.58.6.1072
12. Vasan RS, Levy D, Larson MG, Benjamin EJ. Interpretation of echocardiographic measurements: A call for standardization. Am Heart J. 2000;139(3):412-422. doi:10.1016/S0002-8703(00)90084-X
13. Poelaert J, Declerck C, Vogelaers D, Colardyn F, Visser CA. Left ventricular systolic and diastolic function in septic shock. Intensive Care Med. 1997;23(5):553-560. doi:10.1007/s001340050372
14. Nakamura A, Rokosh DG, Paccanaro M, et al. LV systolic performance improves with development of hypertrophy after transverse aortic constriction in mice. Am J Physiol Hear Circ Physiol. 2001;281(3):H1104-12.
15. Dokainish H. Left ventricular diastolic function and dysfunction: Central role of echocardiography. Glob Cardiol Sci Pract. 2015;2015:3. doi:10.5339/gcsp.2015.3
16. Stewart KC, Kumar R, Charonko JJ, Ohara T, Vlachos PP, Little WC. Evaluation of LV diastolic function from color M-mode echocardiography. JACC Cardiovasc
Imaging. 2011;4(1):37-46. doi:10.1016/j.jcmg.2010.09.020
17. Bierig SM, Hill J. Echocardiographic evaluation of diastolic function. J Diagnostic Med Sonogr. 2011;27(2):65-78. doi:10.1177/8756479311401914
18. Dr. Manish K. Bansal, Dr. Prashant Prakash, Dr. Prabhat K. Agrawal, Dr. Varun Gupta, Assessment of Left Ventricular Systolic/Diastolic Function By Echocardiography In Seropositive HIV Otherwise Asymptomatic Patients. Med Res Chron Med Res Chronicles. 2014;1(2):221-227.
How to Cite
1.
Dr. Prashant Prakash, Dr. Ashwini K. Nigam, Dr. Abhishek Raj, Dr. Prabhat K. Agrawal, Dr. Ashish Gautam, Dr. Nikhil Purasnani. ASSESSMENT OF LEFT VENTRICULAR FUNCTIONS BY ECHOCARDIOGRAPHY TO STUDY THE EFFECTS OF 8-12 WEEKS OF TREATMENT IN THYROID PATIENTS. Med. res. chronicles [Internet]. 1 [cited 2024Apr.24];5(01):91-100. Available from: https://medrech.com/index.php/medrech/article/view/293
Section
Original Research Article
