NMDA ENCEFALITIS CASE REPORT AND LITERATURE REVIEW

  • Najada Como Department of Infectious Disease Hospital, UHC Mother Theresa
  • Migena Qato Department of Infectious Disease Hospital, UHC Mother Theresa
  • Dhimiter Kraja Department of Infectious Disease Hospital, UHC Mother Theresa
  • Drini Dobi Departament of Neurology, UHC Mother Theresa
  • Pellumb Pipero Department of Infectious Disease Hospital, UHC Mother Theresa
  • Arjan Harxhi Department of Infectious Disease Hospital, UHC Mother Theresa
Keywords: encephalitis, NMDA-receptor, psychiatric disorders, autoimmune

Abstract

Encephalitis has many causes, but for most patients, the cause still remains unknown. Worldwide, up to 85% of cases are of unknown cause, and there is concern about new and emerging triggers. N-methyl-D-aspartate receptor (anti-NMDA-R) encephalitis is an immunemediated syndrome that remains under-recognized despite a growing body of literature.[1,2] This syndrome has been predominantly described in young females with a constellation of symptoms, including personality changes, autonomic dysfunction, and neurologic decompensation. It is commonly associated with mature ovarian teratomas.[3] We describe the classic presentation of anti-NMDA-R encephalitis in a young woman, with antecedents in psychiatric disorders which is hospitalized in the Infectious Disease Hospital, UHC Mother Theresa with the admission diagnosis: Acute Viral Encephalitis. We reviewed the literature summarizing the differential diagnosis, investigative approach and therapeutic options related to this disorder[4,5]. We succeed to give good supportive care and involve multiple health disciplines. This case highlights the need for increased awareness and high diagnostic suspicion when approaching the patient with suspected viral encephalitis.

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References

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How to Cite
1.
Najada Como, Migena Qato, Dhimiter Kraja, Drini Dobi, Pellumb Pipero, Arjan Harxhi. NMDA ENCEFALITIS CASE REPORT AND LITERATURE REVIEW. Med. res. chronicles [Internet]. 2018Jun.30 [cited 2024Mar.29];5(3):186-90. Available from: https://medrech.com/index.php/medrech/article/view/304
Section
Case Report