POSTOPERATIVE NAUSEA AND VOMITING EFFECTS OF PROPOFOL AND THIOPENTONE ANAESTHESIA AFTER CHOLECYSTECTOMY AND RECOVERY FROM IT: A COMPARATIVE STUDY

  • Dr. Charan Singh Senior Consultant, Anaesthesia, Malkhan Singh Hosital, Aligarh, India
  • Dr. Supriya Senior Resident, Department of Anaesthesiology and Critical Care, S N Medical College, Agra, India
  • Dr. A. K. Nigam Associate Professor, S N Medical College, Agra, India
  • Dr. Prabhat Agrawal Associate Professor, S N Medical College, Agra, India
Keywords: PONV, Nausea and Vomiting, emesis, antiemetic, anesthesia, propofol, thiopentone and halothane

Abstract

Postoperative nausea, vomiting, retching and other emetic sequel were found to be the most prevalent cause of morbidity after anesthesia and surgery. Postoperative nausea and vomiting if become forceful can produce some very serious side effects like it can cause tension on suture line, can cause hypertension. Any effective clinical anesthetic which can lower or free from such side effects will certainly be the choice of anesthesia. Present study was also aimed to compare the score of emesis sequel and recovery of patients from anesthesia between the patients given with Propofol and conventional anesthetics (Thiopentone + Halothane). Total of 64 adult, ASA Grade I and II patients of either sex, scheduled for elective mini cholecystectomy were enrolled in the study. The patients were randomly divided into two groups consisting 32 patients in each group. Group-I was given Propofol as anesthetic whereas the other Group-II received Thiopentone and Halothane. All the patients were observed for any emesis sequence and its protraction. Mean emesis score and score for the recovery from the anesthesia were recorded. Group of the patients given with Propofol showed more incidence of nausea (21.88%) when compared to Group-II (15.63%) in first 2 hrs, whereas later during 2-24 hrs it becomes more in Group-I (15.63) when comparison to Group-II (3.12%). Incidences of Retching and only Vomiting were found more in Group-I when compared to Group-II at every interval of observation. Also, it was reported that the overall recovery score was higher in case of patients anaesthetized with Propofol.

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How to Cite
1.
Dr. Charan Singh, Dr. Supriya, Dr. A. K. Nigam, Dr. Prabhat Agrawal. POSTOPERATIVE NAUSEA AND VOMITING EFFECTS OF PROPOFOL AND THIOPENTONE ANAESTHESIA AFTER CHOLECYSTECTOMY AND RECOVERY FROM IT: A COMPARATIVE STUDY. Med. res. chronicles [Internet]. 2018Jun.30 [cited 2024Nov.29];5(3):237-45. Available from: https://medrech.com/index.php/medrech/article/view/309
Issue
Vol. 5 No. 3 (2018): May-Jun
Section
Original Research Article