MRSA: THE EVOLVING PATHOGEN, RECENT TRENDS IN DIAGNOSIS AND TREATMENT.

  • Anant Parasher Senior Resident, Department of Medicine, Guru Teg Bahadur Hospital, Delhi, India
  • Kunal Ranjan Senior Resident, Department of Medicine, Guru Teg Bahadur Hospital, Delhi, India
Keywords: Staphylococcus aureus, Antimicrobials MRSA, Penicillin-binding protein

Abstract

MRSA is often used to describe multi-drug resistant Staphylococcus aureus. Resistance is mediated by a gene (mecA) that encodes the production of an altered penicillin-binding protein (PBP2a), which does not allow for the binding of ß-lactams to the bacterial cell wall, because ß-lactams exert antibacterial activity by binding and inhibiting enzymes necessary for bacterial cell wall synthesis, so these antimicrobials are not effective against MRSA. While infection control initiatives have stemmed the rising prevalence, MRSA remains a significant pathogen with its classified strains such as MRSA (CAMRSA & HA-MRSA), VRSA (VISA-Intermediate & VRSA), MSSA, EMRSA (In Epidemiological settings), LA-MRSA (Live Stock).

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How to Cite
1.
Anant Parasher, Kunal Ranjan. MRSA: THE EVOLVING PATHOGEN, RECENT TRENDS IN DIAGNOSIS AND TREATMENT. Med. res. chronicles [Internet]. 1 [cited 2023Feb.9];6(1):10-9. Available from: https://medrech.com/index.php/medrech/article/view/361
Section
Original Research Article