CORONARY MYOCARDIAL BRIDGE, A LONG TERM FOLLOW UP STUDY

  • C. K. Das Central Hospital, South East Central Railway, Bilaspur, Chhattisgarh
  • R. L. Bhanja Central Hospital, South East Central Railway, Bilaspur, Chhattisgarh
  • G. K. Chakraborty Central Hospital, South East Central Railway, Bilaspur, Chhattisgarh
Keywords: Coronary Myocardial bridge, Coronary Artery disease, Nicorandil

Abstract

Myocardial bridging is a congenital anomaly in which a segment of a coronary artery takes a “tunneled” intramuscular course under a “bridge” of overlying myocardium. This causes vessel compression in systole, resulting in hemodynamic changes that may be associated with angina, myocardial ischemia, acute coronary syndrome, left ventricular dysfunction, arrhythmias, and even sudden cardiac death. India is being laden with increasing incidences of coronary heart disease out from clinical presentation through a simplified investigation profile their morbidity may be addressed in a distinguished manner which has a less malignant course of progression. The present study is designed with an objective to identify the clinical spectrum of presentation of coronary myocardial bridge and to evaluate such cases with simple conventional noninvasive and invasive tests. All cases of angina attending the medical and cardiology OPD for the first time at the central hospital, S.E.C. Railway, Bilaspur (CG) between April 2011 to March 2016. After basic investigations all angina cases were evaluated by resting ECG and Echocardiography. Cases with normal resting Echo study were subjected to Tread Mill Test (TMT) with Bruce protocol. Total 1362 (female =354) cases of angina attended for first time in OPD. Out of which 271 (72%) cases had atherosclerotic coronary artery disease (CAD), 61(16%) cases were having CMB and 43 (12%) cases had normal coronaries. 54 patients out of 61 of CMB remained free of symptoms where as 29 out of 43 cases of CAD on medical management. First-line therapy involves medical treatment with betablockers and non-dihydropyridine calcium-channel blockers. From the present study, the researchers observed better results with betablockers added with nikorandil. A prospective randomized trial is required to identify the best treatment strategy for patients with myocardial bridging.

Downloads

Download data is not yet available.

References

1. Lee MS, Chen C-H. 2015 Myocardial Bridging: An Up-to-Date Review. J Invasive Cardiol. 27(11):521-528. http://www.ncbi.nlm.nih.gov/pubmed/25999138. Accessed March 17, 2019.
2. Konen E, Goitein O, Sternik L, Eshet Y, Shemesh J, Di Segni E. 2007 The Prevalence and Anatomical Patterns of Intramuscular Coronary Arteries. J Am Coll Cardiol. 49(5):587-593. doi:10.1016/j.jacc.2006.09.039
3. Ge J, Jeremias A, Rupp A, et al. 1999 New signs characteristic of myocardial bridging demonstrated by intracoronary ultrasound and Doppler. Eur Heart J. 20(23):1707-1716. doi:10.1053/euhj.1999.1661
4. Schwarz ER, Klues HG, vom Dahl J, Klein I, Krebs W, Hanrath P. 1997 Functional characteristics of myocardial bridging. A combined angiographic and intracoronary Doppler flow study. Eur Heart J. 18(3):434-442. http://www.ncbi.nlm.nih.gov/pubmed/9076380. Accessed March 17, 2019.
5. Escaned J, Cortés J, Flores A, et al. 2003 Importance of diastolic fractional flow reserve and dobutamine challenge in physiologic assessment of myocardialbridging. J Am Coll Cardiol. 42(2):226- 233. http://www.ncbi.nlm.nih.gov/pubmed/12875756. Accessed March 17, 2019.
6. Alegria JR, Herrmann J, Holmes DR, Lerman A, Rihal CS. 2005 Myocardial bridging. Eur Heart J. 26(12):1159-1168. doi:10.1093/eurheartj/ehi203
7. Möhlenkamp S, Hort W, Ge J, Erbel R. 2002 Update on myocardial bridging.Circulation. 106(20):2616-2622. http://www.ncbi.nlm.nih.gov/pubmed/12427660. Accessed March 17, 2019.
8. Arjmand Shabestari A, Azma R, Nourmohammad A, Shakiba M. 2016 Systolic Compression of a Myocardial Bridged Coronary Artery and its Morphologic haracteristics: A Combination Study of Computed Tomography Angiography and Invasive Angiography. Iran J Radiol. 13(4). doi:10.5812/iranjradiol.31647
9. Risse M, Weiler G. 1985 [Coronary muscle bridge and its relations to local coronary sclerosis, regional myocardial ischemia and coronary spasm. A morphometric study]. Z Kardiol. 74(12):700-705.Das C. K. et al., Med. Res. Chronicles., 6(2), 58-63 2019 http://www.ncbi.nlm.nih.gov/pubmed/4096063. Accessed March 17, 2019.
10. Mohiddin SA, Begley D, Shih J, Fananapazir L. 2000 Myocardial bridging does not predict sudden death in children with hypertrophic cardiomyopathy but isassociated with more severe cardiac disease. J Am Coll Cardiol. 36(7):2270- 2278.http://www.ncbi.nlm.nih.gov/pubmed/11127472. Accessed March 17, 2019.
11. La Grutta L, Runza G, Lo Re G, et al. 2009 Prevalence of myocardial bridging and correlation with coronary atherosclerosis studied with 64-slice CT coronary angiography. Radiol Med. 114(7):1024-1036. doi:10.1007/s11547-009-0446-y
12. Soran O, Pamir G, Erol C, Kocakavak C, Sabah I. 2000 The incidence and significance of myocardial bridge in a prospectively defined population of patients undergoing coronary angiography for chest pain. Tokai J Exp Clin Med. 25(2):57-60. http://www.ncbi.nlm.nih.gov/pubmed/11127508. Accessed March 17, 2019.
13. Krishnan MN. 2012 Coronary heart disease and risk factors in India - on the brink of an epidemic? Indian Heart J. 64(4):364-367. doi:10.1016/j.ihj.2012.07.001
14. Langdorf MI, Wei E, Ghobadi A, Rudkin SE, Lotfipour S. 2010 Echocardiography to supplement stress electrocardiography in emergency department chest pain patients. West J Emerg Med. 11(4):379-383. http://www.ncbi.nlm.nih.gov/pubmed/21079713. Accessed March 17, 2019.
15. Masuda T, Ishikawa Y, Akasaka Y, Itoh K, Kiguchi H, Ishii T. 2001 The effect of myocardial bridging of the coronary artery on vasoactive agents andatherosclerosis localization. J Pathol. 193(3):408-414. doi:10.1002/1096-9896(2000)9999:9999<::AIDPATH792>3.0.CO;2-R
16. Schwarz ER, Klues HG, vom Dahl J, Klein I, Krebs W, Hanrath P. 1996 Functional, angiographic and intracoronary Doppler flow characteristics in symptomatic patients with myocardial bridging: effect of shortterm intravenous beta-blocker medication. J Am Coll Cardiol. 27(7):1637-1645. http://www.ncbi.nlm.nih.govpubmed/8636548. Accessed March 17, 2019.
17. Alessandri N, Dei Giudici A, De
Angelis S, Urciuoli F, Garante MC, Di
Matteo A. 2012 Efficacy of calcium
channel blockers in the treatment of the
myocardial bridging: a pilot study. Eur
Rev Med Pharmacol Sci. 16(6):829-834.
http://www.ncbi.nlm.nih.gov/pubmed/229
13217. Accessed March 17, 2019.
18. Jung J-H, Min P-K, Sung CW, et al.
2009 The Effect of Intracoronary
Nicorandil on Coronary Myocardial
Bridging. J Cardiovasc Pharmacol Ther.
14(3):180-184. doi: 10.1177/
1074248409338930
How to Cite
1.
C. K. Das, R. L. Bhanja, G. K. Chakraborty. CORONARY MYOCARDIAL BRIDGE, A LONG TERM FOLLOW UP STUDY. Med. res. chronicles [Internet]. 2019Apr.30 [cited 2024Apr.20];6(2):58-3. Available from: https://medrech.com/index.php/medrech/article/view/369
Section
Original Research Article