Role of nanotechnology in oral cancer diagnosis and therapeutics

  • Supriya Sharma Senior Resident, Dept of Oral Pathology and Microbiology, Faculty of Dental Sciences, King George’s Medical University, UP, Lucknow
  • Pradakhshana Vijay Senior Resident, Dept of Oral Pathology and Microbiology, Faculty of Dental Sciences, King George’s Medical University (KGMU), UP, Lucknow
  • Pankaj Kumar Pathak Senior Resident, Dept. of Community and Family Medicine, AIIMS, Patna
  • Priyanka Singh Assistant Professor, Dept of Oral Pathology and Microbiology, Faculty of Dental Sciences, King George’s Medical University (KGMU), UP, Lucknow
  • Surya Kant Prof and Head, Dept of Respiratory Medicine, King George’s Medical University (KGMU), UP, Lucknow
Keywords: Nanoparticles, Nanotechnology, Oral cancer

Abstract

Oral cancer is a multifactorial disease, but tobacco is considered as the most predominant attribute for its advancement. It can be preventable by the interruption of risk factors. Its early detection can minimize its detrimental effects and can improve the quality of life as well as morbidity and mortality of the patients. Nanotechnology is a very different field that has transformed the industry and is setting new directions in the treatment of oral cancer. Nanotechnology conversed methods can be used in cancer treatment. They can aid to have a better diagnosis with limited injurious substance. Nanotechnology is a very different field that has revolutionized the industry and is setting current directions in the management of oral cancer. The application of Nanotechnology significantly benefits clinical practice in diagnosis, treatment, and management of cancer. Hence, Nanotechnology can be also accustomed to molecular imaging accompanied by tomography and photoacoustic imaging of tumors and management of cancer as photothermal and radiotherapy. Nanotechnology a succeeding generation techniques have numerous advantages to treat patients of cancer from diagnosis to treatment.

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References

Wanga Y, Qian X, Zhua X, Chen W, Zhang J, Chena W. Oral cancer-derived exosomal NAP1 enhances the cytotoxicity of natural killer cells via the IRF-3 pathway. Oral Cancer 2018;76:34-41.

Ram H, Sarkar J, Kumar H, Konwar R, Bhatt MLB, Mohammad S Oral Cancer: Risk Factors and Molecular Pathogenesis J. Maxillofac. Oral Surg 2011;10(2):132–137

Alok A, Sunil P, Aggarwal A, Upadhyay N, Agarwal N, Kishore M. Nanotechnology: A boon in oral cancer diagnosis and therapeutics. SRM J Res Dent Sci 2013;4:154-60.

McNeil SE. Nanotechnology for the biologist. J Leukoc Biol 2005;78:585-94.

Grodzinski P, Silver M, Molnar LK. Nanotechnology for cancer diagnostics: Promises and challenges. Expert Rev Mol Diagn 2006;6:307-18.

Rao SB, Bhushanam K, Das UN, Prasad TNVKV, Subbarao K. Recent advances of nanoparticles in cancer therapy and diagnosis. J Med Sci Res 2013; 1(2):95-10

Pisani P, Parkin DM, Bray F, Ferlay J. Estimates of the worldwide mortality from 25 cancers in 1990. Int J Cancer 1999;83:18-29.

Bhardwaj A, Bhardwaj A, Misuriya A, Maroli S, Manjula S, Singh AK, et al. Nanotechnology in dentistry: Present and future. J Int Oral Health 2014;6:1216.

Misra R, Acharya S, Sahoo SK. Cancer nanotechnology: Application of nanotechnology in cancer therapy. Drug Discov Today.2010 ;15(19-20):842-50.

Jaishree V, Gupta PD. Nanotechnology: A Revolution in cancer diagnosis. Indian J Clin Biochem 2012;27:21420.

Saravana KR, Vijayalakshmi R. Nanotechnology in dentistry. Indian J Dent Res 2006;17:625.

Poonia M, Ramalingam K, Goyal S, Sidhu SK. Nanotechnology in oral cancer: A comprehensive review. J Oral Maxillofac Pathol 2017;21:407-14.

Virupakshappa B. Applications of nanomedicine in oral cancer. Oral Health Dent Manag 2012;11:628.

Brigger I, Dubernet C, Couvreur P. Nanoparticles in cancer therapy and diagnosis. Adv Drug Deliv Rev 2002;54:63151.

Hui NC. Nanomedicine and Cancer. This StudentProduced Report is Part of a Larger Pamphlet on Nanotechnologies Circa 2005, the Partial Output of a Course on “Nanotechnology and Society” (Science and Technology Studies, Section 84405, by C. Tahan) Which was Taught in the Spring Semester of 2005 at the University of WisconsinMadison;2005.

Ravindran R. Nanotechnology in cancer diagnosis and treatment: An overview. Oral Maxillofac Pathol J 2011;2:1016.

Rossi B, Schinzari G, Maccauro G, Scaramuzzo L, Signorelli D, Rosa MA, et al. Neoadjuvant multidrug chemotherapy including highdose methotrexate modifies VEGF expression in osteosarcoma: An immunohistochemical analysis. BMC Musculoskelet Disord 2010;11:34-38.

Liboiron BD, Mayer LD. Nanoscale particulate systems for multidrug delivery: Towards improved combination chemotherapy. Ther Deliv 2014;5:14971.

Abbasi MM, Jahanban‑Esfahlan R, Monfaredan A, Seidi K, Hamishehkar H, Khiavi MM, et al. Oral and IV dosages of doxorubicin‑methotrexate loaded‑ nanoparticles inhibit the progression of oral cancer by down-regulation of matrix metalloproteinase 2 expressions in vivo. Asian Pac J Cancer Prev 2014;15:10705‑11.

Nguyen S, Hiorth M. Advanced drug delivery systems for local treatment of the oral cavity. Ther Deliv 2015;6:595‑608.

How to Cite
1.
Supriya Sharma, Pradakhshana Vijay, Pankaj Kumar Pathak, Priyanka Singh, Surya Kant. Role of nanotechnology in oral cancer diagnosis and therapeutics. Med. res. chronicles [Internet]. 2019Aug.31 [cited 2024Apr.19];6(4):192-9. Available from: https://medrech.com/index.php/medrech/article/view/387
Section
Review Article