Prevalence of thyroid dysfunction in type 2 diabetes mellitus patients in Saharanpur, Uttar Pradesh, India.

  • Anil Kumar Garg Department of Medicine, S.M.M.H. Medical College, Saharanpur, Uttar Pradesh, India
  • Virendra Singh Saini Department of Medicine, S.M.M.H. Medical College, Saharanpur, Uttar Pradesh, India
  • Satyanand Sathi Department of Medicine, S.M.M.H. Medical College, Saharanpur, Uttar Pradesh, India
  • Prabhat Agrawal Department of Medicine, S.N. Medical College, Agra, Uttar Pradesh, India
  • Atul Kumar Department of Medicine, S.M.M.H. Medical College, Saharanpur, Uttar Pradesh, India
  • Prabhat Vats Department of Medicine, S.M.M.H. Medical College, Saharanpur, Uttar Pradesh, India
  • Anurag Tomer Department of Medicine, S.M.M.H. Medical College, Saharanpur, Uttar Pradesh, India
  • Shubhra Sharma Department of Medicine, S.M.M.H. Medical College, Saharanpur, Uttar Pradesh, India
  • Jagmohan Department of Medicine, S.M.M.H. Medical College, Saharanpur, Uttar Pradesh, India
  • Ashwarya Gupta Department of Medicine, S.M.M.H. Medical College, Saharanpur, Uttar Pradesh, India
  • Dilli Raman Panhaur Department of Medicine, S.M.M.H. Medical College, Saharanpur, Uttar Pradesh, India
Keywords: Type 2 Diabetes Mellitus, Thyroid, TSH, Thyroid Dysfunction, Prevalence

Abstract

As per World Health Organization (WHO) data - India, China and USA are among the top three countries with a high number of diabetic populations. In 2015 there were about 69.2 million patients (7.8%) affected with type 2 diabetes mellitus in India. Thyroid dysfunction was more common in type 2 diabetes mellitus subjects as compared to nondiabetics. Both diseases influence each other in several ways. Treatment of diabetic patient becomes very difficult when both thyroid disorder and diabetes mellitus exist together. Present study is designed to estimate the prevalence of thyroid dysfunction in type 2 diabetes mellitus subjects along with other biochemical parameters. Among the diabetic group 109 patients and 120 patients in control group were found to be euthyroid. Higher prevalence of thyroid dysfunction was found in patients with type 2 diabetes mellitus, 19.26% patients in Group I and 9.77% patients in Group II were found to have thyroid dysfunction. A routine assessment of thyroid function test should be performed for patients with type 2 diabetes mellitus.

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References

Tusié Luna MT. Genes and Type 2 Diabetes Mellitus. Arch Med Res. 2005;36(3):210-222. doi:10.1016/j.arcmed.2005.03.004

Prasad R, Groop L. Genetics of Type 2 Diabetes—Pitfalls and Possibilities. Genes(Basel). 2015;6(1):87-123. doi:10.3390/genes6010087

Busch C, Hegele R. Genetic determinants of type 2 diabetes mellitus. Clin Genet. 2002;60(4):243-254. doi:10.1034/j.1399- 0004.2001.600401.x

Zhang P, Zhang X, Brown J, et al. Global healthcare expenditure on diabetes for 2010 and 2030. Diabetes Res Clin Pract. 2010;87(3):293-301. doi:10.1016/j.diabres.2010.01.026

Ramachandran A, Snehalatha C. Current scenario of diabetes in India. J Diabetes. 2009;1(1):18-28. doi:10.1111/j.1753- 0407.2008.00004.x

Brenta G. Diabetes and thyroid disorders. Br J Diabetes Vasc Dis. 2010;10(4):172- 177. doi:10.1177/1474651410371321

Kadiyala R, Peter R, Okosieme OE. Thyroid dysfunction in patients with diabetes: clinical implications and screening strategies. Int J Clin Pract. 2010;64(8):1130-1139. doi:10.1111/j.1742-1241.2010.02376.x

Mullur R, Liu YY, Brent GA. Thyroid hormone regulation of metabolism. Physiol Rev. 2014;94(2):355-382. doi:10.1152/physrev.00030.2013

Becker DJ. The Endocrine Responses to Protein Calorie Malnutrition. Annu Rev Nutr. 1983;3(1):187-212. doi:10.1146 /annurev.nu.03.070183.001155

Alsowaidi S, Mohamed A, Bernsen R, Abdulle A, Bener A. Characteristics, severity and management of insect-stung patients. Biomed Res - India. 2009;20(3):155. doi:10.4103/0970-938x.54833

Lingidi JL, Mohapatra E, Doddigarla Z, Kumari S. Serum Lipids and Oxidative Stress in Hypothyroidism Prevalence of Metabolic Syndrome and Its Association with Various Risk Factors View Project Organophosphate Poisoning View Project.; 2012. https://www.researchgate.net/publication/284262982. Accessed November 17, 2019.

Unnikrishnan A, Bantwal G, John M, Kalra S, Sahay R, Tewari N. Prevalence of hypothyroidism in adults: An epidemiological study in eight cities of India. Indian J Endocrinol Metab. 2013;17(4):647. doi:10.4103/2230-8210.113755

Khurana A, Dhoat P, Jain G. Prevalence of thyroid disorders in patients of type 2 diabetes mellitus. Journal, Indian Acad Clin Med. 2016;17(1):12-15. doi:10.1007/s12291-012-0293-9

Laakso M, Pyörälä K. Adverse effects of obesity on lipid and lipoprotein levels in insulin-dependent and non-insulin-dependent diabetes. Metabolism. 1990;39(2):117-122. doi:10.1016/0026-0495(90)90062-h

Wang C. The relationship between type 2 diabetes mellitus and related thyroid diseases. J Diabetes Res. 2013;2013. doi:10.1155/2013/390534

Grassetto G, Rubello D. Thyroid disorders and diabetes mellitus. Minerva Med. 2008;99(3):263-267. doi:10.4061/2011/439463

Perros P, McCrimmon RJ, Shaw G, Frier BM. Frequency of Thyroid Dysfunction in Diabetic Patients: Value of Annual Screening. Diabet Med. 1995;12(7):622-627. doi:10.1111/j.1464-5491.1995.tb00553.x

Chubb SAP, Davis WA, Inman Z, Davis TME. Prevalence and progression of subclinical hypothyroidism in women with type 2 diabetes: the Fremantle Diabetes Study. Clin Endocrinol (Oxf). 2005;62(4):480-486. doi:10.1111/j.1365-2265.2005.02246.x

How to Cite
1.
Anil Kumar Garg, Virendra Singh Saini, Satyanand Sathi, Prabhat Agrawal, Atul Kumar, Prabhat Vats, Anurag Tomer, Shubhra Sharma, Jagmohan, Ashwarya Gupta, Dilli Raman Panhaur. Prevalence of thyroid dysfunction in type 2 diabetes mellitus patients in Saharanpur, Uttar Pradesh, India. Med. res. chronicles [Internet]. 2019Dec.31 [cited 2024Dec.22];6(6):292-8. Available from: https://medrech.com/index.php/medrech/article/view/402
Issue
Vol. 6 No. 6 (2019): Nov-Dec
Section
Original Research Article