Melioidosis: A case series from a tertiary care hospital in Assam

  • Dr Vandana Sinha
  • Dr Anup Jyoti Dutta
  • Dr Partha Pratim Kalita Consultant
  • Dr Himadri Dutta
  • Dr Pinku Sarma
  • Dr Pranab Barua
  • Dr Prerit Sarma
Keywords: Melioidosis, abscess, sepsis, alcoholism, diabetes

Abstract

Melioidosis is sporadically reported from various parts of India. We present a case series from Assam, highlighting the varied manifestations of the disease. Three cases of culture-proven melioidosis are presented in whom Burkholderia pseudomallei were isolated from aspirate or blood. Melioidosis had a varied presentation involving multiple abscesses in the soft tissues, liver, spleen, mediastinum, and the subdural space. It presented as either acute fulminant sepsis or followed a chronic indolent course, mimicking tuberculosis. Most cases had predisposing risk factors such as diabetes and chronic alcoholism.

 

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References

Currie BJ. Burkholderia pseudomallei and Burkholderia mallei: Melioidosis and Glanderschapter 221. In: Principles and Practice of Infectious diseases. 7th ed. Mandel, Douglas and Bennett. London: Churchill Livingstone; 2010. p. 2869-79.

Jesudason MV, Kumari RS, John TJ. Burkholderia pseudomallei‑An emerging pathogen in India. Indian J Med Microbiol 1997;15:1‑2.

Mukhopadhya A, Balaji V, Jesudason MV, Amte A, Jeyamani R, Kurian G. Isolated liver abscesses in melioidosis. Indian J Med Microbiol 2007;25:150‑1

Limmothurohakul D, Golding N, Messina JP et al- Predicted global distribution of B. pseudomallei and burden of meiloidosis. Nat Microbial 2016; 1:15008. DOI 10.1038/nmicrobial.2015.8.

White NJ. Melioidosis. Lancet 2003;361:1715‑22.

Vidyalakshmi KS, Shrikala B, Bharathi B, Suchitra U. Melioidosis: An under-diagnosed entity in western coastal India: A clinico-microbiological analysis. Indian J MedMicrobiol 2007;25:245–48.

Mukhopadhyay C, Chawla K, Krishna S, Nagalakshmi N, Rao SP, Bairy I. Emergence of Burkholderia pseudomallei and pandrug-resistant non-fermenters from southern Karnataka, India. Trop Med Hyg 2008; 102: S12–17.

Mukhopadhya A, Balaji V, Jesudason MV, Amte A, Jeyamani R, Kurian G. Isolated liver abscesss in melioidosis. Indian J Med Microbiol 2007;25:150–51.

CITATION
DOI: 10.26838/MEDRECH.2020.7.6.467
Published: 2020-12-27
How to Cite
1.
Dr Vandana Sinha, Dr Anup Jyoti Dutta, Dr Partha Pratim Kalita, Dr Himadri Dutta, Sarma P, Dr Pranab Barua, Dr Prerit Sarma. Melioidosis: A case series from a tertiary care hospital in Assam. Med. res. chronicles [Internet]. 2020Dec.27 [cited 2024Nov.21];7(6):355-60. Available from: https://medrech.com/index.php/medrech/article/view/467
Section
Case Report