Pediatric multiple sclerosis – A case report from Albania

  • Armand Shehu University Hospital Center “Mother Theresa”, Tirana, Albania
  • Ervin Toçi University Hospital Center “Mother Theresa”, Tirana, Albania
Keywords: Albania, acute disseminated encephalomyelitis, childhood, multiple sclerosis, pediatric


Multiple sclerosis (MS) is one of the most debilitating diseases with a considerable financial burden and deteriorating effect on the quality of life for the affected individual, the family and the entire society. Although MS affects young adults, it can develop in children as well. In these cases, the diagnosis of MS could be rather challenging but it should be timely done in order to start the appropriate treatment and avoid unfavorable outcomes. We present the case of multiple sclerosis in a 13-year-old boy in Albania who initially was suspected to be affected by acute disseminated encephalomyelitis and describe the diagnosis procedure challenges.


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National Multiple Sclerosis Society. What is MS. Available at: Last accessed: June 2020.

Wootla B, Eriguchi M, Rodriguez M. Is multiple sclerosis an autoimmune disease? Autoimmune Dis. 2012; 2012:969657.

Martin R, Sospedra M, Rosito M, Engelhardt B. Current multiple sclerosis treatments have improved our understanding of MS autoimmune pathogenesis. Eur J Immunol. 2016;46(9):2078-2090.

Tillery EE, Clements JN, Howard Z. What's new in multiple sclerosis? Ment Health Clin. 2018;7(5):213-220.

Alroughani R, Boyko A. Pediatric multiple sclerosis: a review. BMC Neurol. 2018 ;18(1) :27.

de Albuquerque RC, de Paula RS, Brito MM, Filho JR, Meguins LC. Pediatric multiple sclerosis-a challenging demyelinating disease: case report and brief review of the literature. Case Rep Pediatr. 2012; 2012:684064.

Fernando KTM, James M. Early predictors of rapidly evolving multiple sclerosis: A case report. J Neuroimmunol. 2017; 307:42-46.

Maroney M, Hunter SF. Implications for multiple sclerosis in the era of the Affordable Care Act: a clinical overview. Am J Manag Care. 2014;20(11 Suppl): S220-S227.

Svendsen B, Grytten N, Bø L, Aarseth H, Smedal T, Myhr KM. The economic impact of multiple sclerosis to the patients and their families in Norway. Eur J Health Econ. 2018;19(9):1243-1257.

Rahmlow MR, Kantarci O. Fulminant demyelinating diseases. Neurohospitalist. 2013;3(2):81-91.

Lee YJ. Acute disseminated encephalomyelitis in children: differential diagnosis from multiple sclerosis on the basis of clinical course. Korean J Pediatr. 2011;54(6):234-240.

Chabas D, Strober J, Waubant E. Pediatric multiple sclerosis. Curr Neurol Neurosci Rep. 2008;8(5):434-441.

Yeshokumar AK, Narula S, Banwell B. Pediatric multiple sclerosis. Curr Opin Neurol. 2017;30(3):216-221.

Batur-Caglayan HZ, Irkec C, Yildirim-Capraz I, Atalay-Akyurek N, Dumlu S. A case of multiple sclerosis and celiac disease. Case Rep Neurol Med. 2013; 2013:576921.

Edwards LJ, Constantinescu CS. A prospective study of conditions associated with multiple sclerosis in a cohort of 658 consecutive outpatients attending a multiple sclerosis clinic. Mult Scler. 2004;10(5):575-581.

Ponsonby AL, Dwyer T, van der Mei I, et al. Asthma onset prior to multiple sclerosis and the contribution of sibling exposure in early life. Clin Exp Immunol. 2006 ;146(3) :463-470.

Bjørnevik K, Riise T, Casetta I, et al. Sun exposure and multiple sclerosis risk in Norway and Italy: The EnvIMS study. Mult Scler. 2014;20(8):1042-1049.

Kampman MT, Wilsgaard T, Mellgren SI. Outdoor activities and diet in childhood and adolescence relate to MS risk above the Arctic Circle. J Neurol. 2007;254(4):471-477.

Sintzel MB, Rametta M, Reder AT. Vitamin D and Multiple Sclerosis: A Comprehensive Review. Neurol Ther. 2018;7(1):59-85.

Maroney M, Hunter SF. Implications for multiple sclerosis in the era of the Affordable Care Act: a clinical overview. Am J Manag Care. 2014;20(11 Suppl): S220-S227.

Waubant E. Improving outcomes in multiple sclerosis through early diagnosis and effective management. Prim Care Companion CNS Disord. 2012;14(5):PCC.11016co2cc.

DOI: 10.26838/MEDRECH.2020.8.2.484
Published: 2021-04-27
How to Cite
Shehu A, Toçi E. Pediatric multiple sclerosis – A case report from Albania. Med. res. chronicles [Internet]. 2021Apr.27 [cited 2021May16];8(2):120-3. Available from:
Case Report