Five-year spatiotemporal distribution of malaria in hotspot and Ivermectin mass-drug administration zone of Amhara Regional State, Ethiopia

  • Chalachew Yenew Social and Population Health (SPH) Unit, Debre Tabor University, Ethiopia
  • Sileshi Mulatu College of Medicine and Health Sciences, Bahir Dar University, Ethiopia
Keywords: Malaria Trend, Ivermectin, Mass-drug Administration, Ethiopia


Objectives: Evaluate the Spatiotemporal distribution of malaria in the hotspot and Ivermectin mass-drug administration Zone of Amhara Regional State, Ethiopia. Study Design: A descriptive prevalence study design was used.

Methods: - A 25 study sources were incorporated in the survey. Purposive sampling techniques were utilized. Data were obtained by the standard format of systematic evaluation of four surveillance units from January to August 2020 through observation, document review, and interviewing surveillance officers and focal persons using a semi-structured Survey. The statistical analysis, tabular, and graphical output are generated using the open-source statistical program R.

Results: - Average report fullness and aptness were 97.9% and 96% respectively. The average annual malaria incidence rate was a decline in terms of place and time, from the year 2015 to 2019 with an average reduction rate of 5.5% and the average annual parasitic incidence rate was 52 (22-199). In 2019/2020, 43,131 malaria cases were reported in the zone. The study identifies no program-specific supportive supervision of public health emergency management and no routine data analysis and was not used for decision making.

Conclusion: This result revealed that the malaria incidence rate showed a remarkable decline. However, the annual parasitic incidence rate remains constant. This indicates that ivermectin did not affect malaria elimination. Hence, the districts and sub-city health offices should conduct regular surveillance data analysis, perform supportive supervision, avail budgets and further laboratory investigations should be done to investigate the effect of ivermectin on the parasites under laboratory conditions.


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How to Cite
Yenew C, Mulatu S. Five-year spatiotemporal distribution of malaria in hotspot and Ivermectin mass-drug administration zone of Amhara Regional State, Ethiopia. Med. res. chronicles [Internet]. 2021Jul.21 [cited 2021Jul.27];8(4):305-12. Available from:
Original Research Article