A clinicopathological study of thyroid swelling
Abstract
Patients with a thyroid swelling present with a mass in the midline neck but can have a varied etiology thus posing a diagnostic challenge. Thyroid swellings are responsible for a significant cause of mortality and morbidity in India. Various benign and malignant lesions are usually found in the thyroid. The present study is done from June 2013 to August 2014. The present study is designed to study Histopathology evaluation of thyroid masses. And to study the etiopathogenesis of the thyroid mass. 24 cases of thyroid masses visiting ENT OPD were recorded. The provisional diagnosis was established and further investigations in the form of complete blood counts, Serum T3, T4 and TSH, Indirect or fibreoptic laryngoscopy, ultrasonography neck, computed tomography scanning and fine-needle aspiration cytology were done.
Thyroid lumps were more prevalent in women between the ages of 21 and 40, possibly as a result of increased estrogen predominance during pregnancy and in premenopausal women.
Females made up the majority of patients with thyroid swellings (80 percent). Although malignant thyroid growths were uncommon (20%), malignancy should be sought out in every thyroid nodule since cancers might show as well confined nodules in the thyroid.
To identify the cause of thyroid enlargement, a detailed history and thorough examination of the head, neck, and ENT examination with relevant investigations are required. It is critical to rule out malignancy in every case of thyroid enlargement, as males have a higher frequency of malignant swellings.
Downloads
References
2. Popat, V; Vora, D; Shah H. Clinico – Pathological Correlation Of Neck Lesions – A Study Of 103 Cases. Internet J Head Neck Surg [Internet]. 2010;4(2). Available from: https://ispub.com/IJHNS/4/2/4131#
3. McGurit W. Diagnosis and Management Of Masses In The Neck With Special Emphasis On Neoplastic Lesions. Oncology. 1990;4(Chp. 85).
4. Shaheen OH. The management of thyroid swellings. J Laryngol Otol [Internet]. 1984 Feb [cited 2014 Nov 2];98(2):179–86. Available from: http://www.ncbi.nlm.nih.gov/pubmed/6693819
6. Schreiner BYBF, Murphy WT. MALIGNANT NEOPLASMS OF THE THYROID GLAND The age incidence of the patients with malignant thyroids. New York state Inst study Malig Dis. :116–25.
7. Thomas PA. Thyroid adenoma: a clinicopathological study of 121 cases. J Indian Med Assoc [Internet]. 1966 Feb 16 [cited 2014 Nov 9];46(4):189–93. Available from: http://www.ncbi.nlm.nih.gov/pubmed/5905523
8. Soldin OP. Thyroid function testing in pregnancy and thyroid disease: trimester-specific reference intervals. Ther Drug Monit [Internet]. 2006 Feb [cited 2014 Nov 15];28(1):8–11. Available from: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3625634&tool=pmcentrez&rendertype=abstract
9. Chen H, Nicol TL, Zeiger MA, Dooley WC, Ladenson PW, Cooper DS, et al. Hurthie Cell Neoplasms of the Thyroid Are There Factors Predictive of Malignancy ? 1998;227(4):542–6.
10. Cooper DS, Schneyer CR. Follicular and Hürthle cell carcinoma of the thyroid. Endocrinol Metab Clin North Am [Internet]. 1990 Sep [cited 2014 Nov 9];19(3):577–91. Available from: http://www.ncbi.nlm.nih.gov/pubmed/2261907
11. LiVolsi VA, Baloch ZW. Follicular neoplasms of the thyroid: view, biases, and experiences. Adv Anat Pathol [Internet]. 2004 Nov [cited 2014 Nov 9];11(6):279–87. Available from: http://www.ncbi.nlm.nih.gov/pubmed/15505528
12. Blanco Carrera C, Peláez Torres N, García-Díaz JD, Maqueda Villaizan E, Sanz JM, Alvarez Hernández J. [Epidemiological and clinicopathological study of thyroid cancer in east Madrid]. Rev clínica española [Internet]. 2005 Jul [cited 2014 Nov 9];205(7):307–10. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16029755
