EFFECT OF SEASON ON CONTRACTILE PROPERTIES OF CONTROL AND 20 DAYS IMMOBILIZED GASTROCNEMIUS MUSCLES OF UROMASTIX HARDWICKII

  • Syed Najamuddin Farooq Department of Physiology, faculty of Medicine, Umm-Al Qura University Makkah kingdom of Saudi Arabia.
  • Muhammad Abdul Azeem Department of Physiology United Medical College Karachi-Pakistan
  • Abdul Halim Serafi Department of Immunology, Faculty of Medicine, Umm-Al Qura University Makkah, Kingdom of Saudi Arabia
  • Shaikh Muhammad Amir Mustafa Department of Physiology, faculty of Medicine, Umm-Al Qura University Makkah kingdom of Saudi Arabia.
  • Muhammad Irfan Safi Rizvi Department of Physiology, faculty of Medicine, Umm-Al Qura University Makkah kingdom of Saudi Arabia.
Keywords: Immobilization, Uromastix, Skeletal muscles, Season, isometric tension parameters

Abstract

Many workers had reported seasonal changes in the biological activity of various classes of animals including reptile Uromastix hardwickii. However, the effect of season on tension generation ability of immobilized reptilian skeletal muscles is not available in the literature. In this study, we observe the response of Imb. Gastrocnemius (Gas) muscle of Uromastix hardwickii to the seasonal changes in terms of its mechanical characteristics and tension generation ability were obtained from control and Immobilized. Gastrocnemius muscles demonstrated a significant rise in both twitch and tetanic tensions from winter (Dec) to peak summer (Jun) which then fall significantly till the second winter (Dec). Both control and Immobilized muscles represented a rise in their average values of %P°/mS from winter (Dec) to peak summer (Jun) and a fall again till next winter but statistically, this change was found significant only in Immobilized muscles. Whereas, a significant reduction in twitch peak duration was demonstrated by both control and Immobilized muscles from winter (Jan) to peak summer (Jun). However, values of twitch peak duration demonstrated a rise again as the season advances towards the hot and dry month of October. Statistically, this rise was found significant only in control muscles. Our study indicates that Uromastix is capable of resisting immobilization (IMB) induced effects by the help of seasonal changes in the environmental temperature during summer but during winter it remained under the influence of plaster cast Immobilization as well as the season (hibernation) that results in a greater reduction in its tension generation ability.

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How to Cite
1.
Farooq SN, Azeem MA, Serafi AH, Mustafa SMA, Rizvi MIS. EFFECT OF SEASON ON CONTRACTILE PROPERTIES OF CONTROL AND 20 DAYS IMMOBILIZED GASTROCNEMIUS MUSCLES OF UROMASTIX HARDWICKII. Med. res. chronicles [Internet]. 2015Feb.20 [cited 2024May3];2(1):135-47. Available from: https://medrech.com/index.php/medrech/article/view/60
Issue
Vol. 2 No. 1 (2015): Jan-Feb
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Original Research Article