Correlation of serum transaminases with dengue serology

  • Dr. Ranjeet S. Patil Postgraduate, department of Medicine, Dr. BVP RMC, Loni
  • Dr. D. V. Sumesh Reddy Postgraduate, department of Medicine, Dr. BVP RMC, Loni
  • Dr. V. Rasagna Postgraduate, department of Medicine, Dr. BVP RMC, Loni
  • Dr. Abhijeet Mulay Asst. Prof, Department of Medicine, Dr. BVP RMC, Loni
  • Dr. S. Varade Professor, , Department of Medicine, Dr. BVP RMC, Loni
Keywords: dengue serology, serum transaminases, Clinical correlation

Abstract

Aim: Clinical correlation of dengue serology with serum transaminases

Introduction: Dengue, caused by dengue virus, spread by AEDES genus mosquito, is one of the most significant arthropod borne disease. In severe and less severe forms dengue may affect liver enzymes. The goal of this research was to examine and compare dengue serology with serum transaminases.

Methodology: The study comprised of 109 cases for which informed consent was taken and the patients were monitored throughout their hospital stay. Dengue antibody detection was used to confirm dengue infection and serum transaminases were monitored.

Conclusion: All types of dengue infection frequently result in elevated transaminases values with SGOT rising much more thn SGPT. Patients with NS1 antibody + dengue, have significantly higher serum transaminases levels. Also, high SGOT and  SGPT values may be a poor prognostic indication and an early sign of dengue infection.

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References

Srinivas V, Srinivas VR. Dengue Fever: A Review Article. Journal of Evolution of Medical and Dental Sciences 2015;4(29:5048-5058.

Martina BE, Koraka P, Osterhaus AD. Dengue virus pathogenesis: an integrated view. Clin Microbiol Rev 2009; 22: 564-581.

Kumar M, Verma RK, Mishra B. Prevalence of Dengue Fever in Western Uttar Pradesh, India: A Gender-Based Study. Int J Appl Basic Med Res. 2020 Jan-Mar;10(1):8-11. doi: 10.4103/ijabmr.IJABMR_337_18. Epub 2020 Jan 3. PMID: 32002378; PMCID: PMC6967337.

Sachin N. Solanke , Abhay S. Pohekar*, Jayshree A. Pohekar Clinical and laboratory profile of dengue fever: a retrospective study

Chhina, Rajoo Singh, Goyal, Omesh, Chhina, Deepinder Kaur, Goyal, Prerna, Kumar, Raj. et al. (2008).

Liver function tests in patients with dengue viral infection.. WHO Regional Office for South-East Asia.. https://apps.who.int/iris/handle/10665/170475

Kuo CH, Tai DI, Chang-Chien CS, Lan CK, Chiou SS, Liaw YF. Liver biochemical tests and dengue fever. Am J Trop Med Hyg 1992; 47: 265-270.

Parkash O, Almas A, Jafri SM, Hamid S, Akhtar J, Alishah H. Severity of acute hepatitis and its outcome in patients with dengue fever in a tertiary care hospital Karachi, Pakistan (South Asia). BMC Gastroenterol. 2010;10:43.

Chen D, Zhang Y, Wu X, et al. A survey of clinical and laboratory characteristics of dengue fever epidemic from 2014 to 2018 in Guangzhou, China. Ann Palliat Med. 2020;9(1):70-81.

Karoli R, Fatima J, Siddiqi Z, Kazmi KI, Sultania AR. Clinical profile of dengue infection at a teaching hospital in North India. J Infect Dev Ctries 2012; 6(7):551-54.

CITATION
DOI: 10.26838/MEDRECH.2022.9.6.639
Published: 2022-11-23
How to Cite
1.
Patil RS, Reddy DVS, Rasagna V, Mulay A, Varade DS. Correlation of serum transaminases with dengue serology. Med. res. chronicles [Internet]. 2022Nov.23 [cited 2024Dec.22];9(6):442-5. Available from: https://medrech.com/index.php/medrech/article/view/620
Section
Original Research Article