Procedural sedation in ERCP with propofol-ketorolac, propofol-dezocine and propofol -fentanyl: A comparative study
Abstract
Background: The comparative outcomes of ketorolac, dezocine, and fentanyl had been evaluated in 150 healthy patients undergoing endoscopic methods in accordance to a randomized, double-blind protocol. Patients obtained ketorolac or dezocine or fentanyl 5min before procedure. The optimal dose of intravenous ketorolac triomethamine (ketorolac), a non-steroidal anti-inflammatory drug has no longer been decided in children. There are only restrained published data on the use of intravenous ketorolac for pediatric analgesia. Objectives: The aim of this study is to assess the patients with Procedural Sedation in ERCP with Propofol-Ketorolac, Propofol-Dezocine, and Propofol so that such patients can be diagnosed and treated early. Methods: This is an observational study. The study was carried out in the Department of Anaesthesiology, Dhaka Medical College Hospital in Bangladesh for the duration of one year (the period from June 2021 to May 2022). Results: This study shows that the according to the age of 150 Patients aged 18 to 50 years where, 25(16.16%) were 18-30 years, 82(54.67%) were 31-40 years and 43(28.67%) were 41-50 years. According to Propofol-Ketorolac the Intraoperative data of Propofol Dosages, Supplement fentanyl, Operating time, and Anesthesia time were 460±205, 25±39, 55±30 and 62±30 respectively, based on Propofol-Dezocine the Intraoperative data of Propofol Dosages, Supplement fentanyl, Operating time and Anesthesia time were 440±165, 24±35, 56±28 and 65±23 respectively and according to Propofol – Fentanyl the Intraoperative data of Propofol Dosages, Supplement fentanyl, Operating time and Anesthesia time were 473 ± 220, 20 ± 26, 53 ± 38 and 61 ± 37 respectively. Conclusions: Ketorolac appears to examine favorably with fentanyl when administered at some stage in Endoscopic procedures. In distinction to ketorolac, the use of dezocine resulted in an accelerated incidence of postoperative nausea and vomiting, contributing to a prolongation of the discharge time.
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