SEROPREVALENCE OF HEPATITIS-B VIRUS INFECTION IN SLUM POPULATION OF DHAKA CITY, BANGLADESH
Abstract
Background: Hepatitis B virus (HBV) infection is a significant global health concern, particularly in developing countries. While previous studies in Bangladesh have reported varying HBV prevalence rates, data specific to urban slum populations is limited.
Objective: Aim of the study was determine the seroprevalence of HBV infection among slum dwellers in Dhaka City, a population potentially at high risk due to socioeconomic and environmental factors.
Methods: This cross-sectional study was conducted from July 2006 to June 2007, involving 2,000 adults randomly selected from slum clusters in Dhaka city, Bangladesh. Participants completed a structured questionnaire covering socio-demographic information was blood samples were collected and tested for HBsAg using test strips, with positive results confirmed by ELISA.
Results: The study revealed hepatitis-B virus infection seroprevalence of 5.40% among the 2,000 participants (mean age 31.91 ± 11.34 years, 59% female). Knowledge about HBV was notably low, with only 7.06% aware that hepatitis could be caused by an infectious agent and 53.99% unaware of transmission modes. HBV vaccination coverage was extremely low at 2.33%. High-risk behaviors were identified, including receiving injections from unqualified providers (16.96%) and using disposable syringes (20.91%). Significantly, HBsAg positivity was associated with male gender (p=0.002), younger age (mean 28.78 ± 10.78 years, p=0.013), and household water supply (p=0.0001). None of the HBsAg-positive cases had received HBV vaccination (p<0.05).
Conclusion: The study reveals a significant HBV seroprevalence in Dhaka's slum population, coupled with low levels of awareness and preventive behaviors. These findings underscore the urgent need for targeted public health interventions, including education campaigns, accessible vaccination programs, and improved healthcare services tailored to the unique challenges of urban slum communities.
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