Comparative Study of TB Treatment Outcomes Among Non-Diabetics, Controlled Diabetics, and Uncontrolled Diabetic Patients
Abstract
Objectives: This study was done to compare the clinical characteristics, bacteriological pattern and treatment outcomes, among non-diabetics, controlled and uncontrolled diabetics. Theoretical Framework: TB continues to be a major global public health concern, with millions of cases reported annually. While there are treatment regimens with high cure rates, achieving optimal outcomes can be significantly challenged by the presence of co-morbidities like DM. Methods: This study was an observational type of analytical study conducted in the Department of Respiratory Medicine, SNMC Agra. Patients who were sputum positive and registered under NTEP were included in this study, PTB patients were screened for DM using Fasting and 2 hour Post Prandial Blood glucose test and Hba1c. Results and Discussion: Patients with DM both controlled and uncontrolled experienced more severe clinical manifestations, delayed sputum conversion, and poorer treatment outcomes as compared to non-diabetics . There were higher cases of drug resistance, treatment failure, loss to follow-up cases and mortality in uncontrolled diabetics while best Treatment outcomes were observed in Non-Diabetics. Research Implications: Given the growing epidemic of DM worldwide it is necessary to add DM prevention and control strategies to TB control programmes during the course of TB treatment, Proper management of DM with improved glucose control and regular monitoring can affect the treatment outcomes in TB patients, as evidenced in our study. Originality: By meticulously evaluating treatment success rates, and exploring potential influencing factors, this study aims to establish a clearer picture of the link between diabetes control and TB treatment.
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References
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