An Analysis of Risk Factors and Clinical Outcomes of Choledocholithiasis in Patients at a Tertiary Care Hospital in Bangladesh.
Abstract
Background: Choledocholithiasis is a common biliary disorder characterized by the presence of stones in the common bile duct, leading to significant clinical complications and morbidity. This study aims to investigate the clinical profile, risk factors, and symptoms of patients diagnosed with choledocholithiasis at a tertiary care hospital in Bangladesh, with an emphasis on demographic patterns and associated comorbid conditions.
Methods: This cross-sectional study was conducted at Bangladesh Medical University (BMU) between July 2024 and December 2024, involving 170 patients diagnosed with choledocholithiasis. Data were collected through a detailed review of clinical records, which included demographic information, clinical features, lifestyle factors, comorbidities, and symptoms. Patients were also assessed for risk factors such as diet, physical activity, and body composition.
Results: The study sample primarily consisted of patients aged 41-60 years (27.65%), with a female predominance (58.83%). Common risk factors included a non-vegetarian diet (57.64%), a sedentary lifestyle (56.47%), and obesity (48.23%). Comorbidities, including diabetes mellitus (38.82%) and hypertension (32.94%), were also prevalent in the patient population. The most frequently reported symptoms were pain (80%), jaundice (71.76%), and fever (52.94%). Clinical signs, such as tenderness in the right hypochondriac region (91.76%) and icterus (89.41%), were predominant.
Conclusion: This study provides a comprehensive overview of the clinical characteristics and risk factors associated with choledocholithiasis in Bangladesh. The findings suggest the need for targeted interventions to address lifestyle factors, manage comorbidities, and consider gender-based risk stratification in clinical practice. Further studies are needed to assess the long-term impact of these factors on disease progression and patient outcomes.
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